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Anti-α1 Connexin [1A]

Info

Catalogue Number 151523
Applications IHC IF WB
Antigen/Gene or Protein Targets Connexin 43 (Cx43 or α1)
Reactivity Mouse
Relevance Connexins are a large family of proteins which form gap junctions. Gap junctions are cell membrane structures that facilitate direct cell-cell communication. Gap junction communication has been implicated in the patterning and development of vertebrate embryos. Individual connexins show complex spatial and temporal variation in expression patterns. This variation contributes to the control of intercellular signalling.
Host Mouse
Immunogen The peptide, EIKKFKYGIEEH, was coupled at the C-terminal end to bovine thyroglobulin at a final molar ratio peptide:thyroglobulin of 40–60:1.
Subclass IgG
Positive Control Heart & liver tissue from 6 week old mice; Heart tissue expresses predominantly Cx43
Myeloma Used P3X63Ag8.653
Recommended Growing Conditions RPMI 1640 + 10-20% FBS + glutamine (2mM)
Research Area Cell Signaling & Signal Transduction, Neurobiology

References: 8 entries

Gorbe et al. 2007. Exp Cell Res. 313(6):1135-48. PMID: 17331498.

Myoblast proliferation and syncytial fusion both depend on connexin43 function in transfected skeletal muscle primary cultures.

Europe PMC ID: 17331498

Pearson et al. 2005. J Neurosci. 25(46):10803-14. PMID: 16291954.

Gap junctions modulate interkinetic nuclear movement in retinal progenitor cells.

Europe PMC ID: 16291954

Saitongdee et al. 2004. J Histochem Cytochem. 52(5):603-15. PMID: 15100238.

Levels of gap junction proteins in coronary arterioles and aorta of hamsters exposed to the cold and during hibernation and arousal.

Europe PMC ID: 15100238

Wright et al. 2001. Reproduction. 121(1):77-88. PMID: 11226030.

Stage-specific and differential expression of gap junctions in the mouse ovary: connexin-specific roles in follicular regulation.

Europe PMC ID: 11226030


Add a reference

References: 8 entries

Gorbe et al. 2007. Exp Cell Res. 313(6):1135-48. PMID: 17331498.

Myoblast proliferation and syncytial fusion both depend on connexin43 function in transfected skeletal muscle primary cultures.

Europe PMC ID: 17331498

Pearson et al. 2005. J Neurosci. 25(46):10803-14. PMID: 16291954.

Gap junctions modulate interkinetic nuclear movement in retinal progenitor cells.

Europe PMC ID: 16291954

Saitongdee et al. 2004. J Histochem Cytochem. 52(5):603-15. PMID: 15100238.

Levels of gap junction proteins in coronary arterioles and aorta of hamsters exposed to the cold and during hibernation and arousal.

Europe PMC ID: 15100238

Wright et al. 2001. Reproduction. 121(1):77-88. PMID: 11226030.

Stage-specific and differential expression of gap junctions in the mouse ovary: connexin-specific roles in follicular regulation.

Europe PMC ID: 11226030


Add a reference

References: 8 entries

Gorbe et al. 2007. Exp Cell Res. 313(6):1135-48. PMID: 17331498.

Myoblast proliferation and syncytial fusion both depend on connexin43 function in transfected skeletal muscle primary cultures.

Pearson et al. 2005. J Neurosci. 25(46):10803-14. PMID: 16291954.

Gap junctions modulate interkinetic nuclear movement in retinal progenitor cells.

Saitongdee et al. 2004. J Histochem Cytochem. 52(5):603-15. PMID: 15100238.

Levels of gap junction proteins in coronary arterioles and aorta of hamsters exposed to the cold and during hibernation and arousal.

Wright et al. 2001. Reproduction. 121(1):77-88. PMID: 11226030.

Stage-specific and differential expression of gap junctions in the mouse ovary: connexin-specific roles in follicular regulation.


Add a reference


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