Cancer Research Technology
Log in Register
Menu

Anti-Zebrafish gut secretory cell epitopes [FIS 4B7/2]

Invented by Linda Ariza-McNaughton from Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields

Info

Catalogue Number 151517
Applications IHC IF WB
Antigen/Gene or Protein Targets Zebrafish gut secretory cell epitopes
Reactivity Zebrafish
Relevance The transparency of the juvenile zebrafish and its genetic advantages make it an attractive model for the study of intestinal differentiation and renewal. This antibody labels the secretory cells of the zebrafish intestinal epithelium, both mucous and enteroendocrine, corresponding to the class of cells that are lost in MathI mouse mutants (Yang et al, (2001) Science 294: 2155-2158)
Host Mouse
Immunogen Lysate of fish intestine
Subclass IgG1
Molecular Weight (kDa) 35
Myeloma Used Sp2/0-Ag14
Strain Balb/c
Notes Suggested Dilution: 1:200

4B7/2 may be used on formalin fixed gut sections of zebrafish.
Research Area Aquaculture, Cell Cycle, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Developmental Biology, Epigenetics & Nuclear Signalling, Epitope Tags, Stem Cell Biology

References

There are 8 reference entries for this reagent.

View All References

References: 8 entries

Matthews et al. 2008. Dev Dyn. 237(1):124-31. PMID: 18095340.

Transcription factor onecut3 regulates intrahepatic biliary development in zebrafish.

Europe PMC ID: 18095340

Dong et al. 2007. Nat Genet. 39(3):397-402. PMID: 17259985.

Fgf10 regulates hepatopancreatic ductal system patterning and differentiation.

Europe PMC ID: 17259985

Bates et al. 2006. Dev Biol. 297(2):374-86. PMID: 16781702.

Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation.

Europe PMC ID: 16781702

Crosnier et al. 2005. Development. 132(5):1093-104. PMID: 15689380.

Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine.

Europe PMC ID: 15689380


Add a reference

References: 8 entries

Matthews et al. 2008. Dev Dyn. 237(1):124-31. PMID: 18095340.

Transcription factor onecut3 regulates intrahepatic biliary development in zebrafish.

Dong et al. 2007. Nat Genet. 39(3):397-402. PMID: 17259985.

Fgf10 regulates hepatopancreatic ductal system patterning and differentiation.

Bates et al. 2006. Dev Biol. 297(2):374-86. PMID: 16781702.

Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation.

Crosnier et al. 2005. Development. 132(5):1093-104. PMID: 15689380.

Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine.


Add a reference