Anti-Goblet cells [FIS 3G12/3]
Invented by Linda Ariza-McNaughton at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151516 |
| Applications | IHC IF WB |
| Antigen/Gene or Protein Targets | Goblet cells in the posterior part of the zebrafish intestine |
| Reactivity | Zebrafish |
| Relevance | The transparency of the juvenile zebrafish and its genetic advantages make it an attractive model for the study of intestinal differentiation and renewal. Antibody 3G12 marks goblet cells specifically. It labels both the mucus compartment and other parts of the cytoplasm. On Western blots, 3G12 stains diffuse bands, consistent with variably glycosylated antigen(s). 3G12 labelled cells are concentrated in the posterior gut. 3G12 is a marker for mucus-secreting cells in the posterior gut of zebrafish. |
| Host | Mouse |
| Immunogen | Lysate of fish gut intestine |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 175, 120, 70 |
| Myeloma Used | Sp2/0-Ag14 |
| Strain | Balb/c |
| Notes | Recommended for use on formalin fixed gut sections of zebrafish at a dilution of 1:200. |
| Research Area | Aquaculture |
References: 2 entries
Crosnier et al. 2005. Development. 132(5):1093-104. PMID: 15689380.
Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine.
Europe PMC ID: 15689380
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References: 2 entries
Crosnier et al. 2005. Development. 132(5):1093-104. PMID: 15689380.
Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine.
Add a reference
