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Anti-Goblet cells [FIS 3G12/3]


Catalogue Number 151516
Applications IHC IF WB
Antigen/Gene or Protein Targets Goblet cells in the posterior part of the zebrafish intestine
Reactivity Zebrafish
Relevance The transparency of the juvenile zebrafish and its genetic advantages make it an attractive model for the study of intestinal differentiation and renewal. Antibody 3G12 marks goblet cells specifically. It labels both the mucus compartment and other parts of the cytoplasm. On Western blots, 3G12 stains diffuse bands, consistent with variably glycosylated antigen(s). 3G12 labelled cells are concentrated in the posterior gut. 3G12 is a marker for mucus-secreting cells in the posterior gut of zebrafish.
Host Mouse
Immunogen Lysate of fish gut intestine
Subclass IgG1
Molecular Weight (kDa) 175, 120, 70
Myeloma Used Sp2/0-Ag14
Strain Balb/c
Notes Recommended for use on formalin fixed gut sections of zebrafish at a dilution of 1:200.
Research Area Aquaculture

References: 1 entry

Crosnier et al. 2005. Development. 132(5):1093-104. PMID: 15689380.

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