Anti-Zebrafish gut absorptive cell epitopes [FIS 4B7/1]
Invented by Linda Ariza-McNaughton from Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (8)
- Inventor Info
Info
| Catalogue Number | 151511 |
| Applications | IHC IF IP WB |
| Antigen/Gene or Protein Targets | Zebrafish gut absorptive cell epitopes |
| Reactivity | Zebrafish |
| Relevance | The transparency of the juvenile zebrafish and its genetic advantages make it an attractive model for the study of intestinal differentiation and renewal. This antibody labels the brush border / glycocalyx of intestinal absorptive cells (apical ends of microvilli). This antibody is not reactive with goblet cells; thus 4B7/1 can be used as a marker for brush border cells. |
| Host | Mouse |
| Immunogen | Zebrafish intestine |
| Subclass | IgG1 |
| Myeloma Used | Sp2/0-Ag14 |
| Notes | Suggested Dilution: 1:200. FIS 4B7/1 may be used with formalin fixed zebrafish tissues. |
| Research Area | Aquaculture, Cell Cycle, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Developmental Biology, Epigenetics & Nuclear Signalling, Epitope Tags, Stem Cell Biology |
References: 8 entries
Matthews et al. 2008. Dev Dyn. 237(1):124-31. PMID: 18095340.
Transcription factor onecut3 regulates intrahepatic biliary development in zebrafish.
Europe PMC ID: 18095340
Dong et al. 2007. Nat Genet. 39(3):397-402. PMID: 17259985.
Fgf10 regulates hepatopancreatic ductal system patterning and differentiation.
Europe PMC ID: 17259985
Bates et al. 2006. Dev Biol. 297(2):374-86. PMID: 16781702.
Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation.
Europe PMC ID: 16781702
Crosnier et al. 2005. Development. 132(5):1093-104. PMID: 15689380.
Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine.
Europe PMC ID: 15689380
Add a reference
References: 8 entries
Matthews et al. 2008. Dev Dyn. 237(1):124-31. PMID: 18095340.
Transcription factor onecut3 regulates intrahepatic biliary development in zebrafish.
Dong et al. 2007. Nat Genet. 39(3):397-402. PMID: 17259985.
Fgf10 regulates hepatopancreatic ductal system patterning and differentiation.
Bates et al. 2006. Dev Biol. 297(2):374-86. PMID: 16781702.
Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation.
Crosnier et al. 2005. Development. 132(5):1093-104. PMID: 15689380.
Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine.
Add a reference
