Anti-LewisX [BU60]
Invented at University Of Birmingham
- Datasheet
- References (5)
- Inventor Info
Info
| Catalogue Number | 151487 |
| Applications | ELISA FACS IHC IP Fn WB |
| Antigen/Gene or Protein Targets | Lewis X (CD15) |
| Synonyms | Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; ELAM-1 Ligand Fucosyltransferase; FUC-TIV; FCT3A; ELFT; Stage-Specific Embryonic Antigen; Alpha (1,3) Fucosyltransferase; EC 2.4.1.65; Lewis X; SSEA-1; FUTIV; CD15; LeX |
| Reactivity | Human |
| Relevance | Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin’s disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation. |
| Host | Mouse |
| Subclass | IgM |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS |
| Strain | Balb/c |
| Notes | Zhang et al., 1998: mAb BU60 inhibited binding of P-selectin mu chain to HL-60 or U937 cells |
| Research Area | Cancer, Immunology |
References: 5 entries
Kishimoto T.Leucocyte Typing V1. 1998. Garland Publishing, NY.
Carter et al. 1999. Xenotransplantation. 6(2):123-30. PMID: 10431789.
Cross-species reactivity of a panel of antibodies with monkey and porcine tissue.
Europe PMC ID: 10431789
Zhang et al. 1998. Hybridoma. 17(5):445-56. PMID: 9873990.
Fn
Novel monoclonal antibodies to putative selectin carbohydrate ligands that inhibit selectin binding to myeloid cells.
Europe PMC ID: 9873990
Add a reference
References: 5 entries
Kishimoto T.Leucocyte Typing V1. 1998. Garland Publishing, NY.
Carter et al. 1999. Xenotransplantation. 6(2):123-30. PMID: 10431789.
Cross-species reactivity of a panel of antibodies with monkey and porcine tissue.
Zhang et al. 1998. Hybridoma. 17(5):445-56. PMID: 9873990.
Fn
Novel monoclonal antibodies to putative selectin carbohydrate ligands that inhibit selectin binding to myeloid cells.
Add a reference
