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Anti-LewisX [BU60]


Catalogue Number 151487
Applications ELISA FACS IHC IP Fn WB
Antigen/Gene or Protein Targets Lewis X (CD15)
Synonyms Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; ELAM-1 Ligand Fucosyltransferase; FUC-TIV; FCT3A; ELFT; Stage-Specific Embryonic Antigen; Alpha (1,3) Fucosyltransferase; EC; Lewis X; SSEA-1; FUTIV; CD15; LeX
Reactivity Human
Relevance Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin’s disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation.
Host Mouse
Subclass IgM
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS
Strain Balb/c
Notes Zhang et al., 1998: mAb BU60 inhibited binding of P-selectin mu chain to HL-60 or U937 cells
Research Area Cancer, Immunology

References: 3 entries

Kishimoto T.Leucocyte Typing V1. 1998. Garland Publishing, NY.

Carter et al. 1999. Xenotransplantation. 6(2):123-30. PMID: 10431789.

Zhang et al. 1998. Hybridoma. 17(5):445-56. PMID: 9873990.


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