Anti-LewisX [BU28]
Invented at University Of Birmingham
- Datasheet
- References (3)
- Inventor Info
Info
Catalogue Number | 151486 |
Applications | FACS |
Antigen/Gene or Protein Targets | Lewis X (CD15) |
Synonyms | Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; ELAM-1 Ligand Fucosyltransferase; FUC-TIV; FCT3A; ELFT; Stage-Specific Embryonic Antigen; Alpha (1,3) Fucosyltransferase; EC 2.4.1.65; Lewis X; SSEA-1; FUTIV; CD15; LeX |
Reactivity | Human |
Relevance | Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin’s disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation. |
Host | Mouse |
Subclass | IgM |
Myeloma Used | P3/NS1/1-Ag4.1 |
Recommended Growing Conditions | RPMI 1640 + 10% FCS |
Strain | Balb/c |
Notes | Flow cytometry: 1/100-1/200 |
Research Area | Cancer, Immunology |
References: 3 entries
Knapp et al. 1989. Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, Oxford.
Zhang et al. 1998. Hybridoma. 17(5):445-56. PMID: 9873990.
Novel monoclonal antibodies to putative selectin carbohydrate ligands that inhibit selectin binding to myeloid cells.
Europe PMC ID: 9873990
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References: 3 entries
Knapp et al. 1989. Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, Oxford.
Zhang et al. 1998. Hybridoma. 17(5):445-56. PMID: 9873990.
Novel monoclonal antibodies to putative selectin carbohydrate ligands that inhibit selectin binding to myeloid cells.
Add a reference