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Anti-EBNA2 [PE2]


Catalogue Number 151472
Applications IHC IF IP WB ChIP-seq
Antigen/Gene or Protein Targets Epstein Barr Virus Encoded Nuclear Antigen 2 (EBNA2)
Reactivity Human and Virus
Relevance The Epstein-Barr Virus (EBV), also called Human herpesvirus 4 (HHV-4), is a virus of the herpes family and is one of the most common viruses in humans. EBNA2 is one of the few genes of Epstein-Barr virus which are necessary for immortalization of human primary B lymphocytes. The EBNA2 protein acts as a transcriptional activator of several viral and cellular genes.
Host Mouse
Immunogen Recombinant fusion protein against EBNA2The immunogen was a beta-gal fusion protein from plasmid pKH-2A10 that contains aa 341-480 of B95.8 type EBNA2A (Fig 4 in Young et al 1989)
Subclass IgG1
Positive Control Immunohistochemistry (Acetone fixed): EBV positive Raji cell Line. Western blotting: B95-8 cell
Molecular Weight (kDa) 52
Myeloma Used P3X63Ag8.653
Research Area Immunology, Virology

References: 11 entries

David et al. 2017. Haematologica. :. PMID: 28232371.


Wille et al. 2016. J Virol. :. PMID: 28003489.


Wang et al. 2015. J Virol. :. PMID: 26719268.

WB ChIP-seq

Pujals et al. 2015. Autophagy. :. PMID: 26565591.


Gibson et al. 2011. Am J Surg Pathol. 35(6):807-15. PMID: 21552113.

Boshoff et al. 1998. Blood. 91(5):1671-9. PMID: 9473233.

Brink et al. 1997. J Clin Pathol. 50(11):911-8. PMID: 9462239.


Niedobitek et al. 1995. Blood. 86(2):659-65. PMID: 7605996.


Rowe et al. 1991. J Exp Med. 173(1):147-58. PMID: 1845872.


Young et al. 1989. N Engl J Med. 321(16):1080-5. PMID: 2552313.

Young et al. 1988. J Gen Virol. 69 ( Pt 5):1051-65. PMID: 2836550.

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