Anti-BCLAF1, Polyclonal [BCLAF1]
Invented by Prof Neil Perkins from University of Newcastle upon Tyne
Invented at University of Dundee
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151459 |
| Applications | IP WB |
| Antigen/Gene or Protein Targets | BCL2 Associated Transcription Factor 1 (BCLAF1) |
| Reactivity | Human |
| Relevance | BCL2-associated transcription factor 1 (BCLAF1), also known as BTF, is a 920 amino acid protein that localizes to both the nucleus and the cytoplasm. Overexpression of BCLAF1 promotes apoptosis by preventing the transcription of Bcl-2. Bcl-2 is one of many key regulators of apoptosis which are essential for development, tissue homeostasis and protection against foreign pathogens. Four isoforms of BCLAF1 exist due to alternative splicing events. |
| Host | Rabbit |
| Immunogen | Recombinant His-tagged protein fragment of Human BCLAF1 |
| Notes | Suggested Dilution for western blot: 1:3000 |
| Research Area | Apoptosis and Programmed Cell Death, Epigenetics & Nuclear Signalling |
References: 2 entries
Bracken et al. 2008. Cancer Res. 68(18):7621-8. PMID: 18794151.
Regulation of cyclin D1 RNA stability by SNIP1.
Europe PMC ID: 18794151
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References: 2 entries
Bracken et al. 2008. Cancer Res. 68(18):7621-8. PMID: 18794151.
Regulation of cyclin D1 RNA stability by SNIP1.
Add a reference
