Anti-Leu2 [BU88]
Invented at University Of Birmingham
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 151437 |
| Applications | FACS IHC |
| Antigen/Gene or Protein Targets | Leu2 (CD8) |
| Reactivity | Human |
| Relevance | Leu-2 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells. BU88 may be used for the detection of immunoregulatory T cell subset imbalance in autoimmune and immunodeficiency states, categorisation of T cell acute lymphoblastic leukaemia and lymphoblastic lymphoma and T4/T8 ratios in rheumatoid arthritis, multiple sclerosis, etc. |
| Host | Mouse |
| Immunogen | CD8 enriched peripheral blood lymphocytes |
| Subclass | IgG1 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS |
| Strain | Balb/c |
| Notes |
BU88 binds 3 out of 4 types of T Cell. Dilution - FACS: 1/100-1/200 |
| Research Area | Immunology, Stem Cell Biology |
References: 4 entries
Kishimoto T. et al. (Eds.) 1997. Leukocyte Typing VI. Garland Publishing Inc. ISBN-13: 978-0815327455
Leukocyte Typing VI. Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997)
Langermans et al. 2000. J Med Primatol. 29(6):397-401. PMID: 11168830.
Reactivity of human T-lymphocyte-specific antibodies with peripheral blood mononuclear cells and spleen of Aotus azarae ssp. boliviensis (owl monkey).
Europe PMC ID: 11168830
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References: 4 entries
Kishimoto T. et al. (Eds.) 1997. Leukocyte Typing VI. Garland Publishing Inc. ISBN-13: 978-0815327455
Leukocyte Typing VI. Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997)
Langermans et al. 2000. J Med Primatol. 29(6):397-401. PMID: 11168830.
Reactivity of human T-lymphocyte-specific antibodies with peripheral blood mononuclear cells and spleen of Aotus azarae ssp. boliviensis (owl monkey).
Add a reference
