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Anti-Leu2 [BU88]


Catalogue Number 151437
Applications FACS IHC
Antigen/Gene or Protein Targets Leu2 (CD8)
Reactivity Human
Relevance Leu-2 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells. BU88 may be used for the detection of immunoregulatory T cell subset imbalance in autoimmune and immunodeficiency states, categorisation of T cell acute lymphoblastic leukaemia and lymphoblastic lymphoma and T4/T8 ratios in rheumatoid arthritis, multiple sclerosis, etc.
Host Mouse
Immunogen CD8 enriched peripheral blood lymphocytes
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS
Strain Balb/c
Notes BU88 binds 3 out of 4 types of T Cell.

Dilution - FACS: 1/100-1/200
Research Area Immunology, Stem Cell Biology

References: 3 entries

Kishimoto T. et al. (Eds.) 1997. Leukocyte Typing VI. Garland Publishing Inc. ISBN-13: 978-0815327455

Leukocyte Typing VI. Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997)

Langermans et al. 2000. J Med Primatol. 29(6):397-401. PMID: 11168830.

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