Anti-CD44 [BU52]
Invented at University Of Birmingham
- Datasheet
- References (15)
- Inventor Info
Info
| Catalogue Number | 151434 |
| Applications | FACS IHC IF IP WB |
| Antigen/Gene or Protein Targets | CD44 |
| Synonyms | CD44 Molecule; Hematopoietic Cell E- And L-Selectin Ligand; GP90 Lymphocyte Homing/Adhesion Receptor; Chondroitin Sulfate Proteoglycan 8; Extracellular Matrix Receptor III; Heparan Sulfate Proteoglycan; Phagocytic Glycoprotein; Hyaluronate Receptor; Hermes Antigen; ECMR-III; HUTCH-I; Epican; CDW44; MDU2; MDU3; MIC4; LHR; Cell Surface Glycoprotein CD44; Phagocytic Glycoprotein I; Soluble CD44; CSPG8; HCELL; PGP-1; MC56; Pgp1 |
| Reactivity | Human |
| Relevance | A broadly distributed receptor. Variants of CD44 are associated with metastasis. |
| Host | Mouse |
| Immunogen | Hiatt myeloma cells |
| Subclass | IgG1 |
| Myeloma Used | NS0 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS |
| Strain | Balb/c |
| Notes |
Flow Cytometry: Use 10 µl of 1/25-1/100 diuted antibody to label 1x10e6 cells in 100 µl. Immunohistochemistry on Paraffin Sections: 1/100-1/200 (Requires antigen retrieval using heat treatment with citrate buffer pH 6.0 prior to staining of paraffin sections). |
| Research Area | Adhesion, Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology |
References: 15 entries
Knapp W. et al. 1989. Leukocyte Typing IV Oxford University Press
Brown et al. 2005. Exp Cell Res. 303(2):400-14. PMID: 15652352.
Regulation of hyaluronan binding by F-actin and colocalization of CD44 and phosphorylated ezrin/radixin/moesin (ERM) proteins in myeloid cells.
Europe PMC ID: 15652352
Takahashi et al. 2003. Lung Cancer. 41(2):145-53. PMID: 12871777.
Restoration of CD44S in non-small cell lung cancer cells enhanced their susceptibility to the macrophage cytotoxicity.
Europe PMC ID: 12871777
Okamoto et al. 1999. J Biol Chem. 274(36):25525-34. PMID: 10464284.
Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins.
Europe PMC ID: 10464284
Baker et al. 1998. Blood. 92(8):2830-43. PMID: 9763568.
Prolonged phenotypic, functional, and molecular change in group I Burkitt lymphoma cells on short-term exposure to CD40 ligand.
Europe PMC ID: 9763568
Guo et al. 1994. Int Immunol. 6(2):213-21. PMID: 7512372.
Palmitoylation of CD44 interferes with CD3-mediated signaling in human T lymphocytes.
Europe PMC ID: 7512372
Lesley et al. 1993. Adv Immunol. 54:271-335. PMID: 8379464.
CD44 and its interaction with extracellular matrix.
Europe PMC ID: 8379464
Anstee et al. 1991. Immunology. 74(2):197-205. PMID: 1721039.
New monoclonal antibodies in CD44 and CD58: their use to quantify CD44 and CD58 on normal human erythrocytes and to compare the distribution of CD44 and CD58 in human tissues.
Europe PMC ID: 1721039
Add a reference
References: 15 entries
Knapp W. et al. 1989. Leukocyte Typing IV Oxford University Press
Brown et al. 2005. Exp Cell Res. 303(2):400-14. PMID: 15652352.
Regulation of hyaluronan binding by F-actin and colocalization of CD44 and phosphorylated ezrin/radixin/moesin (ERM) proteins in myeloid cells.
Takahashi et al. 2003. Lung Cancer. 41(2):145-53. PMID: 12871777.
Restoration of CD44S in non-small cell lung cancer cells enhanced their susceptibility to the macrophage cytotoxicity.
Okamoto et al. 1999. J Biol Chem. 274(36):25525-34. PMID: 10464284.
Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins.
Baker et al. 1998. Blood. 92(8):2830-43. PMID: 9763568.
Prolonged phenotypic, functional, and molecular change in group I Burkitt lymphoma cells on short-term exposure to CD40 ligand.
Guo et al. 1994. Int Immunol. 6(2):213-21. PMID: 7512372.
Palmitoylation of CD44 interferes with CD3-mediated signaling in human T lymphocytes.
Lesley et al. 1993. Adv Immunol. 54:271-335. PMID: 8379464.
CD44 and its interaction with extracellular matrix.
Anstee et al. 1991. Immunology. 74(2):197-205. PMID: 1721039.
New monoclonal antibodies in CD44 and CD58: their use to quantify CD44 and CD58 on normal human erythrocytes and to compare the distribution of CD44 and CD58 in human tissues.
Add a reference
