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Anti-CD44 [BU52]

Info

Catalogue Number 151434
Applications FACS IHC IF IP WB
Antigen/Gene or Protein Targets CD44
Synonyms CD44 Molecule; Hematopoietic Cell E- And L-Selectin Ligand; GP90 Lymphocyte Homing/Adhesion Receptor; Chondroitin Sulfate Proteoglycan 8; Extracellular Matrix Receptor III; Heparan Sulfate Proteoglycan; Phagocytic Glycoprotein; Hyaluronate Receptor; Hermes Antigen; ECMR-III; HUTCH-I; Epican; CDW44; MDU2; MDU3; MIC4; LHR; Cell Surface Glycoprotein CD44; Phagocytic Glycoprotein I; Soluble CD44; CSPG8; HCELL; PGP-1; MC56; Pgp1
Reactivity Human
Relevance A broadly distributed receptor. Variants of CD44 are associated with metastasis.
Host Mouse
Immunogen Hiatt myeloma cells
Subclass IgG1
Myeloma Used NS0
Recommended Growing Conditions RPMI 1640 + 10% FCS
Strain Balb/c
Notes Flow Cytometry: Use 10 µl of 1/25-1/100 diuted antibody to label 1x10e6 cells in 100 µl.

Immunohistochemistry on Paraffin Sections: 1/100-1/200 (Requires antigen retrieval using heat treatment with citrate buffer pH 6.0 prior to staining of paraffin sections).
Research Area Adhesion, Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology

References: 15 entries

Knapp W. et al. 1989. Leukocyte Typing IV Oxford University Press

Brown et al. 2005. Exp Cell Res. 303(2):400-14. PMID: 15652352.

Regulation of hyaluronan binding by F-actin and colocalization of CD44 and phosphorylated ezrin/radixin/moesin (ERM) proteins in myeloid cells.

Europe PMC ID: 15652352

Takahashi et al. 2003. Lung Cancer. 41(2):145-53. PMID: 12871777.

Restoration of CD44S in non-small cell lung cancer cells enhanced their susceptibility to the macrophage cytotoxicity.

Europe PMC ID: 12871777

Okamoto et al. 1999. J Biol Chem. 274(36):25525-34. PMID: 10464284.

Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins.

Europe PMC ID: 10464284

Baker et al. 1998. Blood. 92(8):2830-43. PMID: 9763568.

Prolonged phenotypic, functional, and molecular change in group I Burkitt lymphoma cells on short-term exposure to CD40 ligand.

Europe PMC ID: 9763568

Guo et al. 1994. Int Immunol. 6(2):213-21. PMID: 7512372.

Palmitoylation of CD44 interferes with CD3-mediated signaling in human T lymphocytes.

Europe PMC ID: 7512372

Lesley et al. 1993. Adv Immunol. 54:271-335. PMID: 8379464.

CD44 and its interaction with extracellular matrix.

Europe PMC ID: 8379464

Anstee et al. 1991. Immunology. 74(2):197-205. PMID: 1721039.

New monoclonal antibodies in CD44 and CD58: their use to quantify CD44 and CD58 on normal human erythrocytes and to compare the distribution of CD44 and CD58 in human tissues.

Europe PMC ID: 1721039


Add a reference

References: 15 entries

Knapp W. et al. 1989. Leukocyte Typing IV Oxford University Press

Brown et al. 2005. Exp Cell Res. 303(2):400-14. PMID: 15652352.

Regulation of hyaluronan binding by F-actin and colocalization of CD44 and phosphorylated ezrin/radixin/moesin (ERM) proteins in myeloid cells.

Europe PMC ID: 15652352

Takahashi et al. 2003. Lung Cancer. 41(2):145-53. PMID: 12871777.

Restoration of CD44S in non-small cell lung cancer cells enhanced their susceptibility to the macrophage cytotoxicity.

Europe PMC ID: 12871777

Okamoto et al. 1999. J Biol Chem. 274(36):25525-34. PMID: 10464284.

Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins.

Europe PMC ID: 10464284

Baker et al. 1998. Blood. 92(8):2830-43. PMID: 9763568.

Prolonged phenotypic, functional, and molecular change in group I Burkitt lymphoma cells on short-term exposure to CD40 ligand.

Europe PMC ID: 9763568

Guo et al. 1994. Int Immunol. 6(2):213-21. PMID: 7512372.

Palmitoylation of CD44 interferes with CD3-mediated signaling in human T lymphocytes.

Europe PMC ID: 7512372

Lesley et al. 1993. Adv Immunol. 54:271-335. PMID: 8379464.

CD44 and its interaction with extracellular matrix.

Europe PMC ID: 8379464

Anstee et al. 1991. Immunology. 74(2):197-205. PMID: 1721039.

New monoclonal antibodies in CD44 and CD58: their use to quantify CD44 and CD58 on normal human erythrocytes and to compare the distribution of CD44 and CD58 in human tissues.

Europe PMC ID: 1721039


Add a reference

References: 15 entries

Knapp W. et al. 1989. Leukocyte Typing IV Oxford University Press

Brown et al. 2005. Exp Cell Res. 303(2):400-14. PMID: 15652352.

Regulation of hyaluronan binding by F-actin and colocalization of CD44 and phosphorylated ezrin/radixin/moesin (ERM) proteins in myeloid cells.

Takahashi et al. 2003. Lung Cancer. 41(2):145-53. PMID: 12871777.

Restoration of CD44S in non-small cell lung cancer cells enhanced their susceptibility to the macrophage cytotoxicity.

Okamoto et al. 1999. J Biol Chem. 274(36):25525-34. PMID: 10464284.

Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins.

Baker et al. 1998. Blood. 92(8):2830-43. PMID: 9763568.

Prolonged phenotypic, functional, and molecular change in group I Burkitt lymphoma cells on short-term exposure to CD40 ligand.

Guo et al. 1994. Int Immunol. 6(2):213-21. PMID: 7512372.

Palmitoylation of CD44 interferes with CD3-mediated signaling in human T lymphocytes.

Lesley et al. 1993. Adv Immunol. 54:271-335. PMID: 8379464.

CD44 and its interaction with extracellular matrix.

Anstee et al. 1991. Immunology. 74(2):197-205. PMID: 1721039.

New monoclonal antibodies in CD44 and CD58: their use to quantify CD44 and CD58 on normal human erythrocytes and to compare the distribution of CD44 and CD58 in human tissues.


Add a reference


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