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Anti-LAT1 [BU53]
RECENTLY UPDATED

Info

Catalogue Number 151426
Applications FACS IHC
Antigen/Gene or Protein Targets Large neutral Amino acid Transporter 1 (LAT1, CD98)
Synonyms Solute Carrier Family 7 Member 5; L-Type Amino Acid Transporter; Integral Membrane Protein E16; CD98 Light Chain; 4F2 Light Chain; MPE16; HLAT1; LAT1; Sodium-Independent Neutral Amino Acid Transporter LAT1; Large Neutral Amino Acids Transporter 1; D16S469E; CD98LC; CD98; E16
Reactivity Human
Relevance LAT1 is expressed on numerous cell types including B cells, activated T cells, monocytes, granulocytes, erythrocytes and endothelial cells. LAT1 is up-regulated on leucocytes in inflammatory lesions, and is strongly expressed by neoplastic cells.
Host Mouse
Immunogen Plasma cell line 8226
Subclass
RECENTLY UPDATED
IgG1
Recommended Growing Conditions RPMI 1640 + 10% FCS
Research Area
RECENTLY UPDATED
Cancer, Cell Signaling & Signal Transduction, Metabolism

References: 9 entries
RECENTLY UPDATED

Cho et al. 2001. Blood. 98(2):374-82. PMID: 11435306.

The functional interactions between CD98, beta1-integrins, and CD147 in the induction of U937 homotypic aggregation.

Europe PMC ID: 11435306

Leukocyte Typing VI 1997 Garland Publishing.

Teixeira et al. 1987. J Biol Chem. 262(20):9574-80. PMID: 3036867.

Primary structure of the human 4F2 antigen heavy chain predicts a transmembrane protein with a cytoplasmic NH2 terminus.

Europe PMC ID: 3036867

Hemler et al. 1982. J Immunol. 129(2):623-8. PMID: 6177771.

Characterization of antigen recognized by the monoclonal antibody (4F2): different molecular forms on human T and B lymphoblastoid cell lines.

Europe PMC ID: 6177771

Haynes et al. 1981. J Immunol. 126(4):1409-14. PMID: 7204970.

Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes.

Europe PMC ID: 7204970


Add a reference

References: 9 entries
RECENTLY UPDATED

Cho et al. 2001. Blood. 98(2):374-82. PMID: 11435306.

The functional interactions between CD98, beta1-integrins, and CD147 in the induction of U937 homotypic aggregation.

Europe PMC ID: 11435306

Leukocyte Typing VI 1997 Garland Publishing.

Teixeira et al. 1987. J Biol Chem. 262(20):9574-80. PMID: 3036867.

Primary structure of the human 4F2 antigen heavy chain predicts a transmembrane protein with a cytoplasmic NH2 terminus.

Europe PMC ID: 3036867

Hemler et al. 1982. J Immunol. 129(2):623-8. PMID: 6177771.

Characterization of antigen recognized by the monoclonal antibody (4F2): different molecular forms on human T and B lymphoblastoid cell lines.

Europe PMC ID: 6177771

Haynes et al. 1981. J Immunol. 126(4):1409-14. PMID: 7204970.

Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes.

Europe PMC ID: 7204970


Add a reference

References: 9 entries
RECENTLY UPDATED

Cho et al. 2001. Blood. 98(2):374-82. PMID: 11435306.

The functional interactions between CD98, beta1-integrins, and CD147 in the induction of U937 homotypic aggregation.

Leukocyte Typing VI 1997 Garland Publishing.

Teixeira et al. 1987. J Biol Chem. 262(20):9574-80. PMID: 3036867.

Primary structure of the human 4F2 antigen heavy chain predicts a transmembrane protein with a cytoplasmic NH2 terminus.

Hemler et al. 1982. J Immunol. 129(2):623-8. PMID: 6177771.

Characterization of antigen recognized by the monoclonal antibody (4F2): different molecular forms on human T and B lymphoblastoid cell lines.

Haynes et al. 1981. J Immunol. 126(4):1409-14. PMID: 7204970.

Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes.


Add a reference


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