Anti-MCM5 [A2.7B10.A12.B8]
Invented at University of Cambridge
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Info
| Catalogue Number | 151419 |
| Applications | IF WB |
| Antigen/Gene or Protein Targets | Mini Chromosome Maintenance protein5 (MCM5) |
| Reactivity | Human |
| Relevance | Mini Chromosome Maintenance protein-5 (MCM5) is a component of the prereplicative complex that is essential for DNA replication. MCM proteins 2-7 form a family of DNA helicases implicated at the initiation step of DNA synthesis. MCM5 expression may be applicable in the detection of a number of cancers including cervical, bladder, lung and oesophageal. |
| Host | Mouse |
| Immunogen | His-tagged human Mcm5 (amino acids 367–582) |
| Subclass | IgG2b |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Notes | Nuclear/cytoplasmic staining is observed with this antibody using immunofluorescence. |
| Research Area | Epigenetics & Nuclear Signalling |
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