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Anti-MCM5 [A2.7A3.F12.A7]


Catalogue Number 151418
Applications IF WB
Antigen/Gene or Protein Targets Mini Chromosome Maintenance protein5 (MCM5)
Reactivity Human
Relevance Mini Chromosome Maintenance protein-5 (MCM5) is a component of the prereplicative complex that is essential for DNA replication. MCM proteins 2-7 form a family of DNA helicases implicated at the initiation step of DNA synthesis. MCM5 expression may be applicable in the detection of a number of cancers including cervical, bladder, lung and oesophageal.
Host Mouse
Immunogen His-tagged human Mcm5 (amino acids 367–582)
Subclass IgG2b
Recommended Growing Conditions DMEM + 5% FCS
Notes Clone is also referred to CRCT5.1.
Research Area Epigenetics & Nuclear Signalling

References: 2 entries

Rakotomalala et al. 2008. J Biol Chem. 283(42):28729-40. PMID: 18693245.

Williams et al. 1998. Proc Natl Acad Sci U S A. 95(25):14932-7. PMID: 9843993.

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