Anti-TAL1 [2TL242]
Invented by Karen Pulford from University of Oxford
Invented at University of Oxford
- Datasheet
- References (8)
- Inventor Info
Info
Catalogue Number | 151404 |
Applications | IHC IF IP WB |
Antigen/Gene or Protein Targets | TAL1 (SCL; TCL5) |
Reactivity | Human |
Relevance | TAL-1 is a member of the helix-loop-helix family of transcription factors. Overexpression of the TAL-1 gene is the most common molecular abnormality found in human T cell leukaemia. |
Host | Mouse |
Immunogen | Recombinant TAL-1 protein |
Subclass | IgG1 kappa |
Myeloma Used | P3/NS1/1-Ag4.1 |
Recommended Growing Conditions | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
Notes | Ultroser G can be used at 1% if the cells are not growing well. |
Research Area | Cancer, Cell Cycle, Developmental Biology, Epigenetics & Nuclear Signalling, Stem Cell Biology |
References: 8 entries
Chetty et al. 1997. J Pathol. 181(3):311-5. PMID: 9155718.
TAL-1 protein expression in vascular lesions.
Europe PMC ID: 9155718
Chetty et al. 1996. J Pathol. 178(3):311-5. PMID: 8778337.
An immunohistochemical study of TAL-1 protein expression in leukaemias and lymphomas with a novel monoclonal antibody, 2TL 242.
Europe PMC ID: 8778337
Bernard et al. 1995. Blood. 85(11):3356-7. PMID: 7756670.
Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain.
Europe PMC ID: 7756670
Pulford et al. 1995. Blood. 85(3):675-84. PMID: 7833471.
Expression of TAL-1 proteins in human tissues.
Europe PMC ID: 7833471
Add a reference
References: 8 entries
Chetty et al. 1997. J Pathol. 181(3):311-5. PMID: 9155718.
TAL-1 protein expression in vascular lesions.
Chetty et al. 1996. J Pathol. 178(3):311-5. PMID: 8778337.
An immunohistochemical study of TAL-1 protein expression in leukaemias and lymphomas with a novel monoclonal antibody, 2TL 242.
Bernard et al. 1995. Blood. 85(11):3356-7. PMID: 7756670.
Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain.
Pulford et al. 1995. Blood. 85(3):675-84. PMID: 7833471.
Expression of TAL-1 proteins in human tissues.
Add a reference