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Anti-TAL1 [2TL242]

Invented by Karen Pulford at University of Oxford

Info

Catalogue Number 151404
Applications IHC IF IP WB
Antigen/Gene or Protein Targets TAL1 (SCL; TCL5)
Reactivity Human
Relevance TAL-1 is a member of the helix-loop-helix family of transcription factors. Overexpression of the TAL-1 gene is the most common molecular abnormality found in human T cell leukaemia.
Host Mouse
Immunogen Recombinant TAL-1 protein
Subclass IgG1 kappa
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Notes Ultroser G can be used at 1% if the cells are not growing well.
Research Area Cancer, Cell Cycle, Developmental Biology, Epigenetics & Nuclear Signalling, Stem Cell Biology

References: 8 entries

Chetty et al. 1997. J Pathol. 181(3):311-5. PMID: 9155718.

TAL-1 protein expression in vascular lesions.

Europe PMC ID: 9155718

Chetty et al. 1996. J Pathol. 178(3):311-5. PMID: 8778337.

An immunohistochemical study of TAL-1 protein expression in leukaemias and lymphomas with a novel monoclonal antibody, 2TL 242.

Europe PMC ID: 8778337

Bernard et al. 1995. Blood. 85(11):3356-7. PMID: 7756670.

Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain.

Europe PMC ID: 7756670

Pulford et al. 1995. Blood. 85(3):675-84. PMID: 7833471.

Expression of TAL-1 proteins in human tissues.

Europe PMC ID: 7833471


Add a reference

References: 8 entries

Chetty et al. 1997. J Pathol. 181(3):311-5. PMID: 9155718.

TAL-1 protein expression in vascular lesions.

Europe PMC ID: 9155718

Chetty et al. 1996. J Pathol. 178(3):311-5. PMID: 8778337.

An immunohistochemical study of TAL-1 protein expression in leukaemias and lymphomas with a novel monoclonal antibody, 2TL 242.

Europe PMC ID: 8778337

Bernard et al. 1995. Blood. 85(11):3356-7. PMID: 7756670.

Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain.

Europe PMC ID: 7756670

Pulford et al. 1995. Blood. 85(3):675-84. PMID: 7833471.

Expression of TAL-1 proteins in human tissues.

Europe PMC ID: 7833471


Add a reference

References: 8 entries

Chetty et al. 1997. J Pathol. 181(3):311-5. PMID: 9155718.

TAL-1 protein expression in vascular lesions.

Chetty et al. 1996. J Pathol. 178(3):311-5. PMID: 8778337.

An immunohistochemical study of TAL-1 protein expression in leukaemias and lymphomas with a novel monoclonal antibody, 2TL 242.

Bernard et al. 1995. Blood. 85(11):3356-7. PMID: 7756670.

Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain.

Pulford et al. 1995. Blood. 85(3):675-84. PMID: 7833471.

Expression of TAL-1 proteins in human tissues.


Add a reference


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