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Anti-Cytokeratin [K20]

Invented by Karen Pulford from University of Oxford
Invented at University of Oxford

Info

Catalogue Number 151390
Applications IHC WB
Antigen/Gene or Protein Targets Cytokeratins of 46, 48, 50, 55, 56, 56.5, 59, 61, 62, 64, 65, 66 and 67 kDa
Reactivity Human
Relevance Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles.
Host Mouse
Immunogen Hair keratin
Subclass IgG2a kappa
Molecular Weight (kDa) 46-67
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Notes Ultroser G can be used at 1% if the cells are not growing well.
Research Area Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction

References

There are 4 reference entries for this reagent.

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References: 4 entries

Pulford et al. 1985. Histopathology. 9(8):825-40. PMID: 2414204.

Gatter et al. 1985. Histopathology. 9(8):805-23. PMID: 2414203.

The characterization of two monoclonal anti-keratin antibodies and their use in the study of epithelial disorders.

Europe PMC ID: 2414204

Human lung tumours: a correlation of antigenic profile with histological type.

Europe PMC ID: 2414203


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References: 4 entries

Pulford et al. 1985. Histopathology. 9(8):825-40. PMID: 2414204.

Gatter et al. 1985. Histopathology. 9(8):805-23. PMID: 2414203.

The characterization of two monoclonal anti-keratin antibodies and their use in the study of epithelial disorders.

Human lung tumours: a correlation of antigenic profile with histological type.


Add a reference