Anti-Cytokeratin [K20]
Invented by Karen Pulford from University of Oxford
Invented at University of Oxford
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 151390 |
| Applications | IHC WB |
| Antigen/Gene or Protein Targets | Cytokeratins of 46, 48, 50, 55, 56, 56.5, 59, 61, 62, 64, 65, 66 and 67 kDa |
| Reactivity | Human |
| Relevance | Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. |
| Host | Mouse |
| Immunogen | Hair keratin |
| Subclass | IgG2a kappa |
| Molecular Weight (kDa) | 46-67 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Notes | Ultroser G can be used at 1% if the cells are not growing well. |
| Research Area | Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction |
References: 4 entries
Pulford et al. 1985. Histopathology. 9(8):825-40. PMID: 2414204.
Gatter et al. 1985. Histopathology. 9(8):805-23. PMID: 2414203.
The characterization of two monoclonal anti-keratin antibodies and their use in the study of epithelial disorders.
Europe PMC ID: 2414204
Human lung tumours: a correlation of antigenic profile with histological type.
Europe PMC ID: 2414203
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References: 4 entries
Pulford et al. 1985. Histopathology. 9(8):825-40. PMID: 2414204.
Gatter et al. 1985. Histopathology. 9(8):805-23. PMID: 2414203.
The characterization of two monoclonal anti-keratin antibodies and their use in the study of epithelial disorders.
Human lung tumours: a correlation of antigenic profile with histological type.
Add a reference
