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Anti-HRX [HRX107]


Catalogue Number 151384
Applications ChIP IHC IF WB
Antigen/Gene or Protein Targets Histone-lysine N-methyltransferase (HRX, MLL, ALL1, Htrx)
Reactivity Human
Relevance The HRX gene (also called MLL, ALL-1 or Htrx) located to chromosome band 11q23 is associated with specific subsets of acute Lukaemia through translocations that that result in its fusion with a variety of heterologous partners
Host Mouse
Immunogen Synthetic peptides corresponding to 839-854 of the HRX protein
Subclass IgM
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Notes Ultroser G can be used at 1% if the cells are not growing well.
Research Area Cancer, Epigenetics & Nuclear Signalling

References: 2 entries

Mueller et al. 2009. PLoS Biol. 7(11):e1000249. PMID: 19956800.

Butler et al. 1997. Blood. 89(9):3361-70. PMID: 9129043.

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