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Anti-EMA [E29]

Invented by Dr Jacqueline Cordell at University of Oxford

Info

Catalogue Number 151381
Applications IHC WB
Antigen/Gene or Protein Targets Epithelial Membrane Antigen (EMA)
Reactivity Human
Relevance Glycoproteins isolated from human milk fat globule membranes, designated epithelial membrane antigen (EMA), have been detected immunohistochemically in most nonneoplastic epithelia and are potentially a highly effective marker for establishing the epithelial nature of neoplastic cells.
Host Mouse
Immunogen Human milk fat globule membrane preparation
Subclass IgG2a
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Notes Ultroser G can be used at 1% if the cells are not growing well.
Research Area Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction

References: 19 entries

A case of a CD56-expressing ectomesenchymal chondromyxoid tumor of the tongue: potential diagnostic usefulness of commonly available CD56 over CD57

IHC

Tissue factor-bearing microparticles and CA19.9: two players in pancreatic cancer-associated thrombosis?

Europe PMC ID: 27404454

Woei-A-Jin et al. 2016. Br J Cancer. :. PMID: 27404454.

IHC

Maxillary carcinosarcoma: Identification of a novel MET mutation in both carcinomatous and sarcomatous components through next generation sequencing.

Europe PMC ID: 25782598

Liu et al. 2015. Breast Cancer Res Treat. 151(2):443-51. PMID: 25953688.

IHC

Habougit et al. 2015. Int J Surg Pathol. :. PMID: 26113666.

IHC

Mediastinal Mature Teratoma With Malignant Carcinomatous Transformation (Somatic-Type Malignancy) With Metastatic Course.

Europe PMC ID: 26113666

Kim et al. 2015. PLoS One. 10(3):e0120296. PMID: 25798919.

Invasive micropapillary mucinous carcinoma of the breast is associated with poor prognosis.

Europe PMC ID: 25953688

Ohlmann et al. 2015. Ann Diagn Pathol. :. PMID: 25990776.

Sclerosing epithelioid fibrosarcoma of the kidney: clinicopathologic and molecular study of a rare neoplasm at a novel location.

Europe PMC ID: 25990776

Genome-wide transcript profiling reveals novel breast cancer-associated intronic sense RNAs.

Europe PMC ID: 25798919

Ando et al. 2015. Head Neck. :. PMID: 25782598.

ten Berge et al. 2001. J Clin Pathol. 54(12):933-9. PMID: 11729213.

MUC1 (EMA) is preferentially expressed by ALK positive anaplastic large cell lymphoma, in the normally glycosylated or only partly hypoglycosylated form.

Europe PMC ID: 11729213

Heyderman et al. 1985. Br J Cancer. 52(3):355-61. PMID: 3899156.

Cordell et al. 1985. Br J Cancer. 52(3):347-54. PMID: 3899155.

A new monoclonal antibody to epithelial membrane antigen (EMA)-E29. A comparison of its immunocytochemical reactivity with polyclonal anti-EMA antibodies and with another monoclonal antibody, HMFG-2.

Europe PMC ID: 3899156

Production of monoclonal antibodies against human epithelial membrane antigen for use in diagnostic immunocytochemistry.

Europe PMC ID: 3899155


Add a reference

References: 19 entries

A case of a CD56-expressing ectomesenchymal chondromyxoid tumor of the tongue: potential diagnostic usefulness of commonly available CD56 over CD57

IHC

Tissue factor-bearing microparticles and CA19.9: two players in pancreatic cancer-associated thrombosis?

Europe PMC ID: 27404454

Woei-A-Jin et al. 2016. Br J Cancer. :. PMID: 27404454.

IHC

Maxillary carcinosarcoma: Identification of a novel MET mutation in both carcinomatous and sarcomatous components through next generation sequencing.

Europe PMC ID: 25782598

Liu et al. 2015. Breast Cancer Res Treat. 151(2):443-51. PMID: 25953688.

IHC

Habougit et al. 2015. Int J Surg Pathol. :. PMID: 26113666.

IHC

Mediastinal Mature Teratoma With Malignant Carcinomatous Transformation (Somatic-Type Malignancy) With Metastatic Course.

Europe PMC ID: 26113666

Kim et al. 2015. PLoS One. 10(3):e0120296. PMID: 25798919.

Invasive micropapillary mucinous carcinoma of the breast is associated with poor prognosis.

Europe PMC ID: 25953688

Ohlmann et al. 2015. Ann Diagn Pathol. :. PMID: 25990776.

Sclerosing epithelioid fibrosarcoma of the kidney: clinicopathologic and molecular study of a rare neoplasm at a novel location.

Europe PMC ID: 25990776

Genome-wide transcript profiling reveals novel breast cancer-associated intronic sense RNAs.

Europe PMC ID: 25798919

Ando et al. 2015. Head Neck. :. PMID: 25782598.

ten Berge et al. 2001. J Clin Pathol. 54(12):933-9. PMID: 11729213.

MUC1 (EMA) is preferentially expressed by ALK positive anaplastic large cell lymphoma, in the normally glycosylated or only partly hypoglycosylated form.

Europe PMC ID: 11729213

Heyderman et al. 1985. Br J Cancer. 52(3):355-61. PMID: 3899156.

Cordell et al. 1985. Br J Cancer. 52(3):347-54. PMID: 3899155.

A new monoclonal antibody to epithelial membrane antigen (EMA)-E29. A comparison of its immunocytochemical reactivity with polyclonal anti-EMA antibodies and with another monoclonal antibody, HMFG-2.

Europe PMC ID: 3899156

Production of monoclonal antibodies against human epithelial membrane antigen for use in diagnostic immunocytochemistry.

Europe PMC ID: 3899155


Add a reference

References: 19 entries

A case of a CD56-expressing ectomesenchymal chondromyxoid tumor of the tongue: potential diagnostic usefulness of commonly available CD56 over CD57

IHC

Tissue factor-bearing microparticles and CA19.9: two players in pancreatic cancer-associated thrombosis?

Woei-A-Jin et al. 2016. Br J Cancer. :. PMID: 27404454.

IHC

Maxillary carcinosarcoma: Identification of a novel MET mutation in both carcinomatous and sarcomatous components through next generation sequencing.

Liu et al. 2015. Breast Cancer Res Treat. 151(2):443-51. PMID: 25953688.

IHC

Habougit et al. 2015. Int J Surg Pathol. :. PMID: 26113666.

IHC

Mediastinal Mature Teratoma With Malignant Carcinomatous Transformation (Somatic-Type Malignancy) With Metastatic Course.

Kim et al. 2015. PLoS One. 10(3):e0120296. PMID: 25798919.

Invasive micropapillary mucinous carcinoma of the breast is associated with poor prognosis.

Ohlmann et al. 2015. Ann Diagn Pathol. :. PMID: 25990776.

Sclerosing epithelioid fibrosarcoma of the kidney: clinicopathologic and molecular study of a rare neoplasm at a novel location.

Genome-wide transcript profiling reveals novel breast cancer-associated intronic sense RNAs.

Ando et al. 2015. Head Neck. :. PMID: 25782598.

ten Berge et al. 2001. J Clin Pathol. 54(12):933-9. PMID: 11729213.

MUC1 (EMA) is preferentially expressed by ALK positive anaplastic large cell lymphoma, in the normally glycosylated or only partly hypoglycosylated form.

Heyderman et al. 1985. Br J Cancer. 52(3):355-61. PMID: 3899156.

Cordell et al. 1985. Br J Cancer. 52(3):347-54. PMID: 3899155.

A new monoclonal antibody to epithelial membrane antigen (EMA)-E29. A comparison of its immunocytochemical reactivity with polyclonal anti-EMA antibodies and with another monoclonal antibody, HMFG-2.

Production of monoclonal antibodies against human epithelial membrane antigen for use in diagnostic immunocytochemistry.


Add a reference


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