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Anti-CR1 [To5]

Invented by Dr Jacqueline Cordell at University of Oxford

Info

Catalogue Number 151360
Applications FACS IHC IF WB
Antigen/Gene or Protein Targets Complement Receptor Type 1 (CR1, CD35)
Reactivity Human
Relevance CR1 is found on many leucocytes and binds C3b and C4b. To5 may be used in studies of immune complex mediated glomerulopathies.
Host Mouse
Immunogen C3b receptor-enriched precipitates from tonsil cell membranes
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Notes Ultroser G can be used at 1% if the cells are not growing well.
Research Area Cancer, Immunology

References: 8 entries

Kremlitzka et al. 2013. Int Immunol. 25(1):25-33. PMID: 22962438.

Complement receptor type 1 (CR1, CD35) is a potent inhibitor of B-cell functions in rheumatoid arthritis patients.

Europe PMC ID: 22962438

Gerdes et al. 1982. Immunology. 45(4):645-53. PMID: 7068171.

Human complement (C3b) receptors defined by a mouse monoclonal antibody.

Europe PMC ID: 7068171

Fearon et al. 1980. J Exp Med. 152(1):20-30. PMID: 6967510.

Identification of the membrane glycoprotein that is the C3b receptor of the human erythrocyte, polymorphonuclear leukocyte, B lymphocyte, and monocyte.

Europe PMC ID: 6967510

Gerdes et al. 1980. Immunology. 39(1):75-84. PMID: 6991397.

Xenoantiserum to human C3 receptors: its preparation and effect on the C3b and C3d receptors of tonsil cells and the C3b receptors of erythrocytes and neutrophils.

Europe PMC ID: 6991397


Add a reference

References: 8 entries

Kremlitzka et al. 2013. Int Immunol. 25(1):25-33. PMID: 22962438.

Complement receptor type 1 (CR1, CD35) is a potent inhibitor of B-cell functions in rheumatoid arthritis patients.

Europe PMC ID: 22962438

Gerdes et al. 1982. Immunology. 45(4):645-53. PMID: 7068171.

Human complement (C3b) receptors defined by a mouse monoclonal antibody.

Europe PMC ID: 7068171

Fearon et al. 1980. J Exp Med. 152(1):20-30. PMID: 6967510.

Identification of the membrane glycoprotein that is the C3b receptor of the human erythrocyte, polymorphonuclear leukocyte, B lymphocyte, and monocyte.

Europe PMC ID: 6967510

Gerdes et al. 1980. Immunology. 39(1):75-84. PMID: 6991397.

Xenoantiserum to human C3 receptors: its preparation and effect on the C3b and C3d receptors of tonsil cells and the C3b receptors of erythrocytes and neutrophils.

Europe PMC ID: 6991397


Add a reference

References: 8 entries

Kremlitzka et al. 2013. Int Immunol. 25(1):25-33. PMID: 22962438.

Complement receptor type 1 (CR1, CD35) is a potent inhibitor of B-cell functions in rheumatoid arthritis patients.

Gerdes et al. 1982. Immunology. 45(4):645-53. PMID: 7068171.

Human complement (C3b) receptors defined by a mouse monoclonal antibody.

Fearon et al. 1980. J Exp Med. 152(1):20-30. PMID: 6967510.

Identification of the membrane glycoprotein that is the C3b receptor of the human erythrocyte, polymorphonuclear leukocyte, B lymphocyte, and monocyte.

Gerdes et al. 1980. Immunology. 39(1):75-84. PMID: 6991397.

Xenoantiserum to human C3 receptors: its preparation and effect on the C3b and C3d receptors of tonsil cells and the C3b receptors of erythrocytes and neutrophils.


Add a reference


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