Anti-CR1 [To5]
Invented by Dr Jacqueline Cordell from University of Oxford
Invented at University of Oxford
- Datasheet
- References (8)
- Inventor Info
Info
| Catalogue Number | 151360 |
| Applications | FACS IHC IF WB |
| Antigen/Gene or Protein Targets | Complement Receptor Type 1 (CR1, CD35) |
| Reactivity | Human |
| Relevance | CR1 is found on many leucocytes and binds C3b and C4b. To5 may be used in studies of immune complex mediated glomerulopathies. |
| Host | Mouse |
| Immunogen | C3b receptor-enriched precipitates from tonsil cell membranes |
| Subclass | IgG1 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Notes | Ultroser G can be used at 1% if the cells are not growing well. |
| Research Area | Cancer, Immunology |
References: 8 entries
Kremlitzka et al. 2013. Int Immunol. 25(1):25-33. PMID: 22962438.
Complement receptor type 1 (CR1, CD35) is a potent inhibitor of B-cell functions in rheumatoid arthritis patients.
Europe PMC ID: 22962438
Gerdes et al. 1982. Immunology. 45(4):645-53. PMID: 7068171.
Human complement (C3b) receptors defined by a mouse monoclonal antibody.
Europe PMC ID: 7068171
Fearon et al. 1980. J Exp Med. 152(1):20-30. PMID: 6967510.
Identification of the membrane glycoprotein that is the C3b receptor of the human erythrocyte, polymorphonuclear leukocyte, B lymphocyte, and monocyte.
Europe PMC ID: 6967510
Gerdes et al. 1980. Immunology. 39(1):75-84. PMID: 6991397.
Xenoantiserum to human C3 receptors: its preparation and effect on the C3b and C3d receptors of tonsil cells and the C3b receptors of erythrocytes and neutrophils.
Europe PMC ID: 6991397
Add a reference
References: 8 entries
Kremlitzka et al. 2013. Int Immunol. 25(1):25-33. PMID: 22962438.
Complement receptor type 1 (CR1, CD35) is a potent inhibitor of B-cell functions in rheumatoid arthritis patients.
Gerdes et al. 1982. Immunology. 45(4):645-53. PMID: 7068171.
Human complement (C3b) receptors defined by a mouse monoclonal antibody.
Fearon et al. 1980. J Exp Med. 152(1):20-30. PMID: 6967510.
Identification of the membrane glycoprotein that is the C3b receptor of the human erythrocyte, polymorphonuclear leukocyte, B lymphocyte, and monocyte.
Gerdes et al. 1980. Immunology. 39(1):75-84. PMID: 6991397.
Xenoantiserum to human C3 receptors: its preparation and effect on the C3b and C3d receptors of tonsil cells and the C3b receptors of erythrocytes and neutrophils.
Add a reference
