Anti-CD20 [PDR78]
Invented by Karen Pulford from University of Oxford
Invented at University of Oxford
- Datasheet
- References (1)
- Inventor Info
Info
| Catalogue Number | 151353 |
| Applications | FACS IHC |
| Antigen/Gene or Protein Targets | CD20 |
| Synonyms | Membrane Spanning 4-Domains A1; Membrane-Spanning 4-Domains Subfamily A Member 1; Leukocyte Surface Antigen Leu-16; CD20 Antigen; CD20; Bp35; B-Lymphocyte Cell-Surface Antigen B1 |
| Reactivity | Human |
| Relevance | CD20 is a non-Ig differentiation antigen of B cells. Oligomer of CD20 act as calcium channels. It may also be involved in B cell activation and cell cycle progression. CD20 is broadly expressed by normal and neoplastic B cells and absent from all other leucocytes and tissues. |
| Host | Mouse |
| Immunogen | Pokeweed mitogen-activated Burkitt's lymphoma cell lines. |
| Subclass | IgG |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Notes | Ultroser G can be used at 1% if the cells are not growing well. |
| Research Area | Cancer, Cell Cycle, Immunology, Stem Cell Biology |
References: 1 entry
Ono N et al. 1997. CD20 Workshop Panel report. In Kishimoto T et al (eds) Leucocyte Typing VI. Garland Publishing Inc., New York and London, p 135-137.
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References: 1 entry
Ono N et al. 1997. CD20 Workshop Panel report. In Kishimoto T et al (eds) Leucocyte Typing VI. Garland Publishing Inc., New York and London, p 135-137.
Add a reference
