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Anti-CD20 [PDR78]

Invented by Karen Pulford at University of Oxford

Info

Catalogue Number 151353
Applications FACS IHC
Antigen/Gene or Protein Targets CD20
Synonyms Membrane Spanning 4-Domains A1; Membrane-Spanning 4-Domains Subfamily A Member 1; Leukocyte Surface Antigen Leu-16; CD20 Antigen; CD20; Bp35; B-Lymphocyte Cell-Surface Antigen B1
Reactivity Human
Relevance CD20 is a non-Ig differentiation antigen of B cells. Oligomer of CD20 act as calcium channels. It may also be involved in B cell activation and cell cycle progression. CD20 is broadly expressed by normal and neoplastic B cells and absent from all other leucocytes and tissues.
Host Mouse
Immunogen Pokeweed mitogen-activated Burkitt's lymphoma cell lines.
Subclass IgG
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Notes Ultroser G can be used at 1% if the cells are not growing well.
Research Area Cancer, Cell Cycle, Immunology, Stem Cell Biology

References: 1 entry

Ono N et al. 1997. CD20 Workshop Panel report. In Kishimoto T et al (eds) Leucocyte Typing VI. Garland Publishing Inc., New York and London, p 135-137.


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References: 1 entry

Ono N et al. 1997. CD20 Workshop Panel report. In Kishimoto T et al (eds) Leucocyte Typing VI. Garland Publishing Inc., New York and London, p 135-137.


Add a reference

References: 1 entry

Ono N et al. 1997. CD20 Workshop Panel report. In Kishimoto T et al (eds) Leucocyte Typing VI. Garland Publishing Inc., New York and London, p 135-137.


Add a reference


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