Anti-LewisX [By87a]
Invented by Karen Pulford from University of Oxford
Invented at University of Oxford
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151350 |
| Applications | FACS IHC IF IP WB |
| Antigen/Gene or Protein Targets | Lewis X (CD15) |
| Synonyms | Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; ELAM-1 Ligand Fucosyltransferase; FUC-TIV; FCT3A; ELFT; Stage-Specific Embryonic Antigen; Alpha (1,3) Fucosyltransferase; EC 2.4.1.65; Lewis X; SSEA-1; FUTIV; CD15; LeX |
| Reactivity | Human |
| Relevance | Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias. Lewis X is commonly used in the diagnosis of Hodgkin's disease. It can also be used for analysis of myeloid leukaemias and the study of myeloid differentiation. |
| Host | Mouse |
| Immunogen | B cell lymphoma cells |
| Subclass | IgM |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Notes | Ultroser G can be used at 1% if the cells are not growing well. |
| Research Area | Cancer, Immunology |
References: 2 entries
Dorfman et al. 1986. Am J Pathol. 123(3):508-19. PMID: 3717303.
An evaluation of the utility of anti-granulocyte and anti-leukocyte monoclonal antibodies in the diagnosis of Hodgkin's disease.
Europe PMC ID: 3717303
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References: 2 entries
Dorfman et al. 1986. Am J Pathol. 123(3):508-19. PMID: 3717303.
An evaluation of the utility of anti-granulocyte and anti-leukocyte monoclonal antibodies in the diagnosis of Hodgkin's disease.
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