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Anti-Integrin aX [KB90]


Catalogue Number 151349
Applications FACS IHC WB
Antigen/Gene or Protein Targets Integrin aX (CD11c; gp150/95 a subunit)
Reactivity Human
Relevance Integrin aX is found on hairy cell leukaemias and malignant histiocytes and on tissue macrophages, monocytes, activated neutrophils and some T-cell clones. Integrin aX has utility for diagnsis of hariy cell leukaemia
Host Mouse
Immunogen Hairy cell leukaemia cells
Subclass IgG1 kappa
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Notes Ultroser G can be used at 1% if the cells are not growing well.
Research Area Adhesion, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology

References: 2 entries

In Schlossman SF, et al (eds) 1995. Leucocyte Typing V, Vol 2 Oxford University Press, Oxford, New York and Tokyo, p 2004

MacDonald et al. 1986. Immunology. 59(3):427-31. PMID: 2431998.

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