Anti-Integrin aX [KB90]
Invented by Karen Pulford from University of Oxford
Invented at University of Oxford
- Datasheet
- References (3)
- Inventor Info
Info
| Catalogue Number | 151349 |
| Applications | FACS IHC WB |
| Antigen/Gene or Protein Targets | Integrin aX (CD11c; gp150/95 a subunit) |
| Reactivity | Human |
| Relevance | Integrin aX is found on hairy cell leukaemias and malignant histiocytes and on tissue macrophages, monocytes, activated neutrophils and some T-cell clones. Integrin aX has utility for diagnsis of hariy cell leukaemia |
| Host | Mouse |
| Immunogen | Hairy cell leukaemia cells |
| Subclass | IgG1 kappa |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Notes | Ultroser G can be used at 1% if the cells are not growing well. |
| Research Area | Adhesion, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology |
References: 3 entries
In Schlossman SF, et al (eds) 1995. Leucocyte Typing V, Vol 2 Oxford University Press, Oxford, New York and Tokyo, p 2004
MacDonald et al. 1986. Immunology. 59(3):427-31. PMID: 2431998.
A monoclonal antibody recognizing the p150/95 leucocyte differentiation antigen.
Europe PMC ID: 2431998
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References: 3 entries
In Schlossman SF, et al (eds) 1995. Leucocyte Typing V, Vol 2 Oxford University Press, Oxford, New York and Tokyo, p 2004
MacDonald et al. 1986. Immunology. 59(3):427-31. PMID: 2431998.
A monoclonal antibody recognizing the p150/95 leucocyte differentiation antigen.
Add a reference
