Anti-Leu2 [X107]
Invented by Karen Pulford from University of Oxford
Invented at University of Oxford
- Datasheet
- References (1)
- Inventor Info
Info
| Catalogue Number | 151346 |
| Applications | FACS IHC |
| Antigen/Gene or Protein Targets | Leu2 (CD8) |
| Synonyms | CD8a Molecule; T-Lymphocyte Differentiation Antigen T8/Leu-2; CD8 Antigen; Alpha Polypeptide (P32); MAL; T-Cell Surface Glycoprotein CD8 Alpha Chain; Leu2 T-Lymphocyte Antigen; OKT8 T-Cell Antigen; T-Cell Antigen Leu2; T8 T-Cell Antigen; CD8a Antigen; Leu2; P32 |
| Reactivity | Human |
| Relevance | Leu-2 (CD8) is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells which make up 30% of circulating T cells. X107 may be used to detect these cells in tissue sections and also their neoplastic counterparts. |
| Host | Mouse |
| Immunogen | Synthetic peptide ( the 13 c-terminal residues of the cytoplasmic domain of human CD8a) |
| Subclass | Not Known |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Notes | Ultroser G can be used at 1% if the cells are not growing well. |
| Research Area | Immunology, Stem Cell Biology |
References: 1 entry
Knapp W. et al. 1989. Leukocyte Typing IV. Oxford University Press. p 1076. ISBN-13: 978-0192618672
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References: 1 entry
Knapp W. et al. 1989. Leukocyte Typing IV. Oxford University Press. p 1076. ISBN-13: 978-0192618672
Add a reference
