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Anti-Leu1 [CD5/54/F6]


Catalogue Number 151343
Applications IHC WB
Antigen/Gene or Protein Targets Leu1 (CD5)
Synonyms CD5 Molecule 2; Lymphocyte Antigen T1/Leu-1; LEU1; CD5 Antigen; T1
Reactivity Bovine, Chicken, Horse, Guinea Pig, Opossum, Pig, Primate, Rat and Rabbit
Relevance CD5 is a surface glycoprotein present on peripheral T cells (>95%) and B-cell chronic lymphocytic leukaemia cells that binds CD72. CD5 has utility for the monitoring of T-cell numbers in peripheral blood and the identification of leukaemias of T cell origin. Absence of the CD5 marker on childhood ALL cells is associated with a more favourable prognosis. Detects CD5 on mammalian tissue
Host Mouse
Immunogen Peptide from the intracellular region of CD5 (SSMQPDNSSDSDYDLHGAQRL)
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Notes Ultroser G can be used at 1% if the cells are not growing well.
Research Area Immunology, Stem Cell Biology

References: 1 entry

Jones et al. 1993. J Immunol. 150(12):5429-35. PMID: 8515069.

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