Anti-Leu1 [CD5/54/F6]

Tool Details

*FOR RESEARCH USE ONLY

• Name: Anti-Leu1 [CD5/54/F6]
• Alternate name: CD5 Molecule 2; Lymphocyte Antigen T1/Leu-1; LEU1; CD5 Antigen; T1
• Clone: CD5/54/F6
• Tool sub type: Primary antibody
• Class: Monoclonal
• Purpose: Marker
• Conjugation: Unconjugated
• Reactivity: Bovine ; Chicken ; Horse ; Guinea Pig ; Opossum ; Pig ; Primate ; Rat ; Rabbit
• Host: Mouse
• Application: IHC ; WB
• Description: CD5 is a surface glycoprotein present on peripheral T cells (>95%) and B-cell chronic lymphocytic leukaemia cells that binds CD72. CD5 has utility for the monitoring of T-cell numbers in peripheral blood and the identification of leukaemias of T cell origin. Absence of the CD5 marker on childhood ALL cells is associated with a more favourable prognosis. Detects CD5 on mammalian tissue
• Immunogen: Peptide from the intracellular region of CD5 (SSMQPDNSSDSDYDLHGAQRL)
• Isotype: IgG1
• Myeloma used: P3/NS1/1-Ag4.1

Target Details

• Target: Leu1 (CD5)
• Tissue cell line specificity: Mouse
• Target background: CD5 is a surface glycoprotein present on peripheral T cells (>95%) and B-cell chronic lymphocytic leukaemia cells that binds CD72. CD5 has utility for the monitoring of T-cell numbers in peripheral blood and the identification of leukaemias of T cell origin. Absence of the CD5 marker on childhood ALL cells is associated with a more favourable prognosis. Detects CD5 on mammalian tissue

Applications

• Application: IHC ; WB

Handling

• Format: Liquid
• Concentration: 0.9-1.1 mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -15° C to -25° C
• Shipping conditions: Shipping at 4° C

References

• Jones et al. 1993. J Immunol. 150(12):5429-35. PMID: 8515069.
• Detection of T and B cells in many animal species using cross-reactive anti-peptide antibodies.