Anti-CD3 [PC3/188A]
Invented by Dr Jacqueline Cordell from University of Oxford
Invented at University of Oxford
- Datasheet
- References (8)
- Inventor Info
Info
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| Catalogue Number | 151342 |
| Applications | IHC WB |
| Antigen/Gene or Protein Targets | CD3 |
| Synonyms | T3 complex |
| Reactivity | Bovine, Chicken, Horse, Guinea Pig, Opossum, Pig, Primate, Rat and Rabbit |
| Relevance | The CD3 complex, composed of five CD3 polypeptide chains, associates with the T cell antigen receptor (TCR) and is found on all mature human T lymphocytes. CD3 can be used for the identification of normal and malignant T lymphocytes in paraffin embedded or frozen tissue sections. PC3/188A also detects CD3 in mammalian tissues. |
| Host | Mouse |
| Immunogen | Peptide sequence (156-168) from the intracytoplasmic portion of the epsilon-chain of CD3 |
| Subclass | IgG1 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) |
| Notes | Ultroser G can be used at 1% if the cells are not growing well. |
| Research Area | Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology |
References: 8 entries
Doursout et al. 2013. J Interferon Cytokine Res. 33(7):376-83. PMID: 23600861.
Inflammatory cells and cytokines in the olfactory bulb of a rat model of neuroinflammation; insights into neurodegeneration?
Europe PMC ID: 23600861
Wang et al. 2012. PLoS One. 7(7):e39525. PMID: 22848356.
Interleukin-10 haplotype may predict survival and relapse in resected non-small cell lung cancer.
Europe PMC ID: 22848356
Bianchi et al. 2012. Diabetes Metab Res Rev. 28(2):156-63. PMID: 21922635.
Oligodeoxynucleotide IMT504: lack of effect on immune parameters during islet regeneration in single dose streptozotocin-induced diabetes.
Europe PMC ID: 21922635
Jones et al. 1993. J Immunol. 150(12):5429-35. PMID: 8515069.
Detection of T and B cells in many animal species using cross-reactive anti-peptide antibodies.
Europe PMC ID: 8515069
Add a reference
References: 8 entries
Doursout et al. 2013. J Interferon Cytokine Res. 33(7):376-83. PMID: 23600861.
Inflammatory cells and cytokines in the olfactory bulb of a rat model of neuroinflammation; insights into neurodegeneration?
Wang et al. 2012. PLoS One. 7(7):e39525. PMID: 22848356.
Interleukin-10 haplotype may predict survival and relapse in resected non-small cell lung cancer.
Bianchi et al. 2012. Diabetes Metab Res Rev. 28(2):156-63. PMID: 21922635.
Oligodeoxynucleotide IMT504: lack of effect on immune parameters during islet regeneration in single dose streptozotocin-induced diabetes.
Jones et al. 1993. J Immunol. 150(12):5429-35. PMID: 8515069.
Detection of T and B cells in many animal species using cross-reactive anti-peptide antibodies.
Add a reference
