Anti-TCP1 [22b]
Invented at The Institute of Cancer Research
- Datasheet
- References (5)
- Inventor Info
Info
| Catalogue Number | 151324 |
| Applications | ELISA IP WB |
| Antigen/Gene or Protein Targets | T-complex polypeptide-1 (TCP1; CCTalpha) |
| Reactivity | Chicken, Dog, Hamster, Mouse and Rat |
| Relevance | TCP1, (a constituent of chaperone-containing TCP-1, CCT) is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells and upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin. |
| Host | Rat |
| Immunogen | C-terminal half of the full length murine TCP protein |
| Subclass | IgG2a |
| Myeloma Used | Y3.AG.1.2.3 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Notes | 22b does not recognise primate, yeast or xenopus TCP-1. 22b is monospecific for TCP-1, not reacting with similar proteins. |
| Research Area | Apoptosis and Programmed Cell Death, Cancer, Cell Cycle |
References: 5 entries
Zhu H et al, 2010. Proteomics (19):3480-93 PMID 20815088
Harrison-Lavoie et al. 1993. EMBO J. 12(7):2847-53. PMID: 8335000.
A 102 kDa subunit of a Golgi-associated particle has homology to beta subunits of trimeric G proteins.
Europe PMC ID: 8335000
Willison et al. 1989. Cell. 57(4):621-32. PMID: 2655925.
The t complex polypeptide 1 (TCP-1) is associated with the cytoplasmic aspect of Golgi membranes.
Europe PMC ID: 2655925
Add a reference
References: 5 entries
Zhu H et al, 2010. Proteomics (19):3480-93 PMID 20815088
Harrison-Lavoie et al. 1993. EMBO J. 12(7):2847-53. PMID: 8335000.
A 102 kDa subunit of a Golgi-associated particle has homology to beta subunits of trimeric G proteins.
Willison et al. 1989. Cell. 57(4):621-32. PMID: 2655925.
The t complex polypeptide 1 (TCP-1) is associated with the cytoplasmic aspect of Golgi membranes.
Add a reference
