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Anti-TCP1 [22b]


Catalogue Number 151324
Applications ELISA IP WB
Antigen/Gene or Protein Targets T-complex polypeptide-1 (TCP1; CCTalpha)
Reactivity Chicken, Dog, Hamster, Mouse and Rat
Relevance TCP1, (a constituent of chaperone-containing TCP-1, CCT) is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells and upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin.
Host Rat
Immunogen C-terminal half of the full length murine TCP protein
Subclass IgG2a
Myeloma Used Y3.AG.1.2.3
Recommended Growing Conditions DMEM + 5% FCS
Notes 22b does not recognise primate, yeast or xenopus TCP-1. 22b is monospecific for TCP-1, not reacting with similar proteins.
Research Area Apoptosis and Programmed Cell Death, Cancer, Cell Cycle

References: 3 entries

Zhu H et al, 2010. Proteomics (19):3480-93 PMID 20815088

Harrison-Lavoie et al. 1993. EMBO J. 12(7):2847-53. PMID: 8335000.

Willison et al. 1989. Cell. 57(4):621-32. PMID: 2655925.

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