Anti-Keratin18 [LDK18]
Invented by Prof Birgit Lane from A*STAR Accelerate Technologies Pte Ltd
Invented at University of Dundee
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 151317 |
| Applications | ELISA FACS IHC IF IP WB |
| Antigen/Gene or Protein Targets | Keratin 18 |
| Reactivity | Human, Mouse and Pig |
| Relevance | Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas. |
| Host | Mouse |
| Immunogen | Synthetic peptide of human keratin 18 (CSETNDTKVLRH-COOH) |
| Positive Control | Simple epithelial cells |
| Subclass | IgG1 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Notes | Use LDK18 undiluted for indirect immunofluorescence assays and immunohistochemistry. This antibody is recommended for immunoblotting applications. |
| Research Area | Cell Signaling & Signal Transduction |
References: 4 entries
D'Alessandro et al. 2011. J Invest Dermatol. 131(7):1412-9. PMID: 21326298.
Keratin 14-null cells as a model to test the efficacy of gene therapy approaches in epithelial cells.
Europe PMC ID: 21326298
Hosoya et al. 2010. Anat Rec (Hoboken). 293(11):1864-72. PMID: 20818615.
Immunohistochemical localization of cytokeratins in the junctional region of ectoderm and endoderm.
Europe PMC ID: 20818615
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References: 4 entries
D'Alessandro et al. 2011. J Invest Dermatol. 131(7):1412-9. PMID: 21326298.
Keratin 14-null cells as a model to test the efficacy of gene therapy approaches in epithelial cells.
Hosoya et al. 2010. Anat Rec (Hoboken). 293(11):1864-72. PMID: 20818615.
Immunohistochemical localization of cytokeratins in the junctional region of ectoderm and endoderm.
Add a reference
