Anti-EB1 [EB1-CL 1A11/4]
Invented at University of Leeds
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 151308 |
| Applications | ELISA IHC IF IP WB |
| Antigen/Gene or Protein Targets | EB1 |
| Reactivity | Human, Primate and Dog |
| Relevance | EB1 is a microtubule tip-associated protein that interacts with the APC tumour suppressor protein and components of the dynein/dynactin complex. |
| Host | Mouse |
| Immunogen | EB1 deltaC1 mutant |
| Positive Control | HeLa cells |
| Subclass | IgG2b |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | CD1 |
| Notes | This antibody recognises a defined epitope which is distinct from the major protein-protein interaction sites. 1A11/4 does not bind EB3 or RP1. |
| Research Area | Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction |
References: 4 entries
Bowen et al. 2011. J Cell Biol. 194(2):187-97. PMID: 21788367.
Septin GTPases spatially guide microtubule organization and plus end dynamics in polarizing epithelia.
Europe PMC ID: 21788367
Askham et al. 2002. Mol Biol Cell. 13(10):3627-45. PMID: 12388762.
Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome.
Europe PMC ID: 12388762
Add a reference
References: 4 entries
Bowen et al. 2011. J Cell Biol. 194(2):187-97. PMID: 21788367.
Septin GTPases spatially guide microtubule organization and plus end dynamics in polarizing epithelia.
Askham et al. 2002. Mol Biol Cell. 13(10):3627-45. PMID: 12388762.
Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome.
Add a reference
