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Anti-EB1 [EB1-CL 1A11/4]

Invented at University of Leeds

Info

Catalogue Number 151308
Applications ELISA IHC IF IP WB
Antigen/Gene or Protein Targets EB1
Reactivity Human, Primate and Dog
Relevance EB1 is a microtubule tip-associated protein that interacts with the APC tumour suppressor protein and components of the dynein/dynactin complex.
Host Mouse
Immunogen EB1 deltaC1 mutant
Positive Control HeLa cells
Subclass IgG2b
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain CD1
Notes This antibody recognises a defined epitope which is distinct from the major protein-protein interaction sites. 1A11/4 does not bind EB3 or RP1.
Research Area Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction

References

There are 4 reference entries for this reagent.

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References: 4 entries

Bowen et al. 2011. J Cell Biol. 194(2):187-97. PMID: 21788367.

Septin GTPases spatially guide microtubule organization and plus end dynamics in polarizing epithelia.

Europe PMC ID: 21788367

Askham et al. 2002. Mol Biol Cell. 13(10):3627-45. PMID: 12388762.

Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome.

Europe PMC ID: 12388762


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References: 4 entries

Bowen et al. 2011. J Cell Biol. 194(2):187-97. PMID: 21788367.

Septin GTPases spatially guide microtubule organization and plus end dynamics in polarizing epithelia.

Askham et al. 2002. Mol Biol Cell. 13(10):3627-45. PMID: 12388762.

Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome.


Add a reference

Inventor Information

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