Anti-EME1 [MTA31 7h2/1]
Invented by Dr Stephen West from Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 151294 |
| Applications | WB |
| Antigen/Gene or Protein Targets | Essential meiotic endonuclease 1 (EME1) |
| Reactivity | Human |
| Relevance | EME1 (aka Msm4) and Mus81 constitute a heterodimeric endonuclease that has been implicated in mitotic and meiotic recombination in eukaryotes. |
| Host | Mouse |
| Immunogen | Human EME1 |
| Positive Control | Recombinant protein, human whole cell extracts, and fractionated cell extracts |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 60-65 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Notes | Suggested Dilution for western blot: 1:1000 |
| Research Area | Cell Cycle, Developmental Biology, Stem Cell Biology |
References: 4 entries
Rass et al. 2010. Genes Dev. 24(14):1559-69. PMID: 20634321.
Mechanism of Holliday junction resolution by the human GEN1 protein.
Europe PMC ID: 20634321
Tomoda et al. 2009. Int J Cancer. 124(12):2997-3001. PMID: 19267403.
Functional evidence for Eme1 as a marker of cisplatin resistance.
Europe PMC ID: 19267403
Add a reference
References: 4 entries
Rass et al. 2010. Genes Dev. 24(14):1559-69. PMID: 20634321.
Mechanism of Holliday junction resolution by the human GEN1 protein.
Tomoda et al. 2009. Int J Cancer. 124(12):2997-3001. PMID: 19267403.
Functional evidence for Eme1 as a marker of cisplatin resistance.
Add a reference
