Cancer Research Technology
Log in Register
Menu

Anti-EME1 [MTA31 7h2/1]

Invented by Dr Stephen West at Francis Crick Institute

Info

Catalogue Number 151294
Applications WB
Antigen/Gene or Protein Targets Essential meiotic endonuclease 1 (EME1)
Reactivity Human
Relevance EME1 (aka Msm4) and Mus81 constitute a heterodimeric endonuclease that has been implicated in mitotic and meiotic recombination in eukaryotes.
Host Mouse
Immunogen Human EME1
Subclass IgG1
Positive Control Recombinant protein, human whole cell extracts, and fractionated cell extracts
Molecular Weight (kDa) 60-65
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Notes Suggested Dilution for western blot: 1:1000
Research Area Cell Cycle, Developmental Biology, Stem Cell Biology

References: 4 entries

Rass et al. 2010. Genes Dev. 24(14):1559-69. PMID: 20634321.

Mechanism of Holliday junction resolution by the human GEN1 protein.

Europe PMC ID: 20634321

Tomoda et al. 2009. Int J Cancer. 124(12):2997-3001. PMID: 19267403.

Functional evidence for Eme1 as a marker of cisplatin resistance.

Europe PMC ID: 19267403


Add a reference

References: 4 entries

Rass et al. 2010. Genes Dev. 24(14):1559-69. PMID: 20634321.

Mechanism of Holliday junction resolution by the human GEN1 protein.

Europe PMC ID: 20634321

Tomoda et al. 2009. Int J Cancer. 124(12):2997-3001. PMID: 19267403.

Functional evidence for Eme1 as a marker of cisplatin resistance.

Europe PMC ID: 19267403


Add a reference

References: 4 entries

Rass et al. 2010. Genes Dev. 24(14):1559-69. PMID: 20634321.

Mechanism of Holliday junction resolution by the human GEN1 protein.

Tomoda et al. 2009. Int J Cancer. 124(12):2997-3001. PMID: 19267403.

Functional evidence for Eme1 as a marker of cisplatin resistance.


Add a reference


This reagent does not have any reviews at the moment.