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Anti-ICAM1 [P1W16]


Catalogue Number 151290
Applications FACS IHC IF IP
Antigen/Gene or Protein Targets ICAM1 (CD54)
Synonyms Intercellular Adhesion Molecule 1; Major Group Rhinovirus Receptor; ICAM-1; Cell Surface Glycoprotein P3.58; Human Rhinovirus Receptor; P3.58; CD54; BB2
Reactivity Human
Relevance ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-1 is expressed in haemopoietic cells and vascular endothelium. Cytokine activation causes ICAM-1 expression in other cell types such as fibroblasts and keratinocytes. ICAM-1 is involved in leukocyte recruitment and inflammation. ICAM-1 binds LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). P1W16 may be useful for prognosis of malignant melanoma.
Host Mouse
Immunogen V(+)B2- Human Ocular melanoma line
Subclass IgG1
Positive Control A375M melanoma or tonsil
Molecular Weight (kDa) 85-115
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Adhesion, Cardiovascular, Immunology, Stem Cell Biology

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