Anti-ICAM1 [P1W16]
Invented at Queen Mary University of London
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Info
| Catalogue Number | 151290 |
| Applications | FACS IHC IF IP |
| Antigen/Gene or Protein Targets | ICAM1 (CD54) |
| Synonyms | Intercellular Adhesion Molecule 1; Major Group Rhinovirus Receptor; ICAM-1; Cell Surface Glycoprotein P3.58; Human Rhinovirus Receptor; P3.58; CD54; BB2 |
| Reactivity | Human |
| Relevance | ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-1 is expressed in haemopoietic cells and vascular endothelium. Cytokine activation causes ICAM-1 expression in other cell types such as fibroblasts and keratinocytes. ICAM-1 is involved in leukocyte recruitment and inflammation. ICAM-1 binds LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). P1W16 may be useful for prognosis of malignant melanoma. |
| Host | Mouse |
| Immunogen | V(+)B2- Human Ocular melanoma line |
| Positive Control | A375M melanoma or tonsil |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 85-115 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Research Area | Adhesion, Cardiovascular, Immunology, Stem Cell Biology |
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