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Anti-Zebrafish DeltaD [zdd2]


Catalogue Number 151283
Antigen/Gene or Protein Targets Zebrafish DeltaD extracellular domain
Reactivity Zebrafish
Relevance Delta proteins activate Notch through a binding reaction that depends on their extracellular domains; they play a key role in the control of cell differentiation by lateral inhibition. DeltaD is widely expressed in subsets of cells in the nervous system, mesoderm, gut, and elsewhere. Deltas associate with membrane-associated scaffolding proteins MAGI1, MAGI2 and MAGI3. This antibody does not detect DeltaC; but it cross-reacts weakly with DeltaA.
Host Mouse
Immunogen Extracellular domain; DeltaD peptide
Subclass IgG1
Positive Control HEK293 cells transfected with deltaD; and zebrafish embryo
Myeloma Used Sp2/0-Ag14
Strain Balb/c
Notes Recommended for use in formalin fixed tissue sections of zebrafish.
Research Area Aquaculture, Cell Cycle, Developmental Biology, Neurobiology

References: 3 entries

Crosnier et al. 2005. Development. 132(5):1093-104. PMID: 15689380.

Wright et al. 2004. Development. 131(22):5659-69. PMID: 15509766.

Itoh et al. 2003. Dev Cell. 4(1):67-82. PMID: 12530964.

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