Anti-Zebrafish DeltaD [zdd2]
Invented by Dr Gavin Wright from Wellcome Trust Sanger Institute
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (10)
- Inventor Info
Info
| Catalogue Number | 151283 |
| Applications | ELISA FACS IHC IF WB |
| Antigen/Gene or Protein Targets | Zebrafish DeltaD extracellular domain |
| Reactivity | Zebrafish |
| Relevance | Delta proteins activate Notch through a binding reaction that depends on their extracellular domains; they play a key role in the control of cell differentiation by lateral inhibition. DeltaD is widely expressed in subsets of cells in the nervous system, mesoderm, gut, and elsewhere. Deltas associate with membrane-associated scaffolding proteins MAGI1, MAGI2 and MAGI3. This antibody does not detect DeltaC; but it cross-reacts weakly with DeltaA. |
| Host | Mouse |
| Immunogen | Extracellular domain; DeltaD peptide |
| Positive Control | HEK293 cells transfected with deltaD; and zebrafish embryo |
| Subclass | IgG1 |
| Myeloma Used | Sp2/0-Ag14 |
| Strain | Balb/c |
| Notes | Recommended for use in formalin fixed tissue sections of zebrafish. |
| Research Area | Aquaculture, Cell Cycle, Developmental Biology, Neurobiology |
References: 10 entries
Sharma et al. 2019. Sci Rep. 9(1):9958. PMID: 31292468.
Tong et al. 2019. Methods Mol Biol. 1576:273-281. PMID: 28434166.
Gallagher et al. 2017. Dev Biol. 429(1):225-239. PMID: 28648842.
Rothschild et al. 2013. Dev Biol. 381(1):179-88. PMID: 23747599.
Wright et al. 2011. Development. 138(14):2947-56. PMID: 21653612.
Fujita et al. 2011. Development. 138(9):1705-15. PMID: 21429985.
Hong et al. 2011. PLoS One. 6(4):e19076. PMID: 21533047.
IHC
Crosnier et al. 2005. Development. 132(5):1093-104. PMID: 15689380.
Wright et al. 2004. Development. 131(22):5659-69. PMID: 15509766.
Itoh et al. 2003. Dev Cell. 4(1):67-82. PMID: 12530964.
Add a reference
References: 10 entries
Sharma et al. 2019. Sci Rep. 9(1):9958. PMID: 31292468.
Tong et al. 2019. Methods Mol Biol. 1576:273-281. PMID: 28434166.
Gallagher et al. 2017. Dev Biol. 429(1):225-239. PMID: 28648842.
Rothschild et al. 2013. Dev Biol. 381(1):179-88. PMID: 23747599.
Wright et al. 2011. Development. 138(14):2947-56. PMID: 21653612.
Fujita et al. 2011. Development. 138(9):1705-15. PMID: 21429985.
Hong et al. 2011. PLoS One. 6(4):e19076. PMID: 21533047.
IHC
Crosnier et al. 2005. Development. 132(5):1093-104. PMID: 15689380.
Wright et al. 2004. Development. 131(22):5659-69. PMID: 15509766.
Itoh et al. 2003. Dev Cell. 4(1):67-82. PMID: 12530964.
Add a reference
