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Anti-XRCC2 [XRCC2 1G4/1]


Catalogue Number 151282
Applications WB
Antigen/Gene or Protein Targets XRay Repair Cross Complementing 2 (XRCC2)
Reactivity Human and Hamster
Relevance X-Ray Repair Cross Complementing 2 (XRCC2) is a RAD51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. XRCC2 is also a component of the homologous recombination pathway.
Host Mouse
Subclass IgG1
Positive Control HeLa nuclear extracts
Molecular Weight (kDa) 33
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Notes XRCC2 1G4/1 does not recognise other paralogs.
Research Area Bacteriology, DNA Damage and Repair, Epigenetics & Nuclear Signalling

References: 3 entries

Gildemeister et al. 2009. J Biol Chem. 284(46):31945-52. PMID: 19783859.

Nagaraju et al. 2009. Mol Cell Biol. 29(15):4283-94. PMID: 19470754.

French et al. 2002. J Biol Chem. 277(22):19322-30. PMID: 11912211.

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