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Catalogue Number 151277
Applications ELISA WB
Antigen/Gene or Protein Targets S100A8 (MRP8)
Reactivity Human
Relevance S100A8 and S100A9 are cytosolic calcium-binding proteins of 8kDa and 14kDa respectively that form a heterodimer. S100A8 and S100A9 are expressed in peripheral blood monocytes, neutrophils and keratinocytes (mature). Expression is lost on tissue maturation of monocytes to macrophages. S100A9 may be associated with monocyte and neutrophil activation and the accumulation of these cells in inflammatory sites.
Host Mouse
Immunogen Recombinant human S100A8
Subclass IgG1
Positive Control Positive control: neutrophil lysate (from spleen)
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Notes 2C5/4 is very specific for S100A8 both as an isolated protein and in combination with S100A9.
Research Area Cancer, Cell Type or Organelle Marker, Neurobiology

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