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Info
| Catalogue Number | 151275 |
| Applications | ELISA IP WB |
| Antigen/Gene or Protein Targets | Activating Protein 2 (AP-2) beta (Human) |
| Reactivity | Human |
| Relevance | AP-2 is a family of developmentally regulated transcription factors which also play a role in breast cancer and melanoma. AP-2ß may be important in cardiac and kidney development. The AP-2 transcription factors form the OB2 complex that has been shown to up-regulate c-erb-B2 transcription. |
| Host | Mouse |
| Immunogen | Truncated AP-2 beta protein prepared from bacteria |
| Positive Control | Human breast cancer line MDA MB 453 |
| Subclass | IgG2b |
| Subclass Notes | Faint cross reactivity with IgG2a |
| Molecular Weight (kDa) | 50 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Notes | Highly recommended for western blot applications. |
| Research Area | Cancer, Cardiovascular, Epigenetics & Nuclear Signalling |
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Inventor Information
Inventors
|
Helen Hurst |
