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Anti-AP2b [AP2bß 1F3/8]


Catalogue Number 151274
Applications ELISA IHC WB
Antigen/Gene or Protein Targets Activating Protein 2 (AP-2) beta
Reactivity Human
Relevance AP-2 is a family of developmentally regulated transcription factors which also play a role in breast cancer and melanoma. AP-2ß may be important in cardiac and kidney development. The AP-2 transcription factors form the OB2 complex that has been shown to up-regulate c-erb-B2 transcription.
Host Mouse
Immunogen Truncated AP-2ß protein prepared from bacteria
Subclass IgG2a
Positive Control Human breast cancer line MDA MB 453
Molecular Weight (kDa) 50
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Notes Antigen recovery using microwave or pressure cooking required for paraffin embedded tissue.
Research Area Cancer, Cardiovascular, Epigenetics & Nuclear Signalling

References: 2 entries

Personal communication.

Ebauer et al. 2007. Oncogene. 26(51):7267-81. PMID: 17525748.

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