Anti-AP2b [AP2bbeta 1F3/8]

Tool Details

*FOR RESEARCH USE ONLY

• Name: Anti-AP2b [AP2bbeta 1F3/8]
• Clone: AP2b? 1F3/8
• Tool sub type: Primary antibody
• Class: Monoclonal
• Conjugation: Unconjugated
• Molecular weight: 50 kDa
• Strain: Balb/c
• Reactivity: Human
• Host: Mouse
• Application: ELISA ; IHC ; WB
• Description: AP-2 is a family of developmentally regulated transcription factors which also play a role in breast cancer and melanoma. AP-2?Ÿ may be important in cardiac and kidney development. The AP-2 transcription factors form the OB2 complex that has been shown to up-regulate c-erb-B2 transcription.
• Immunogen: Truncated AP-2? protein prepared from bacteria
• Isotype: IgG2a
• Myeloma used: Sp2/0-Ag14
• Recommended controls: Human breast cancer line MDA MB 453

Target Details

• Target: Activating Protein 2 (AP-2) beta
• Molecular weight: 50 kDa
• Tissue cell line specificity: Human breast cancer line MDA MB 453
• Target background: AP-2 is a family of developmentally regulated transcription factors which also play a role in breast cancer and melanoma. AP-2? may be important in cardiac and kidney development. The AP-2 transcription factors form the OB2 complex that has been shown to up-regulate c-erb-B2 transcription.

Applications

• Application: ELISA ; IHC ; WB

Handling

• Format: Liquid
• Concentration: 1 mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -15° C to -25° C
• Shipping conditions: Shipping at 4° C

References

• Ebauer et al. 2007. Oncogene. 26(51):7267-81. PMID: 17525748.
• Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR.