Anti-FZR1 [AR38.2]
Invented by Julian Gannon from The Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151251 |
| Applications | ELISA WB |
| Antigen/Gene or Protein Targets | Fizzy Related Protein (FZR1, Cdh1) |
| Synonyms | Fizzy/Cell Division Cycle 20 Related 1; CDC20-Like Protein 1; Cdh1/Hct1 Homolog; CDC20 Homolog 1; HCDH1; CDH1; FZR; CDC20-Like 1b; KIAA1242; CDC20C; FZR2; HCDH; FYR |
| Reactivity | Human and Mouse |
| Relevance | FZR1 is related to Fizzy protein (Cdc20). Both FZR1 and Cdc20 are activators of the anaphase promoting complex (APC), which is responsible for the destruction of many cell cycle related proteins. |
| Host | Mouse |
| Immunogen | His-tagged recombinant Fizzy Related Protein (also known as Cdh1) |
| Subclass | IgG1 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 10% FCS |
| Strain | Balb/c |
| Notes | Recommended concentration: 2.5ug/ml |
| Research Area | Cell Cycle, Protein Degradation |
References: 2 entries
Holt et al. 2010. Development. 137(8):1297-304. PMID: 20223764.
Spatial regulation of APCCdh1-induced cyclin B1 degradation maintains G2 arrest in mouse oocytes.
Europe PMC ID: 20223764
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References: 2 entries
Holt et al. 2010. Development. 137(8):1297-304. PMID: 20223764.
Spatial regulation of APCCdh1-induced cyclin B1 degradation maintains G2 arrest in mouse oocytes.
Add a reference
