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Anti-p14 ARF [ARF 4C6/4]

Info

Catalogue Number 151246
Applications ELISA IHC IF IP WB
Antigen/Gene or Protein Targets p14 ARF
Reactivity Human
Relevance p14ARF is associated with the regulation of p53 and MDM2 and is deleted or methylated in many human cancers.
Host Mouse
Immunogen His-tagged p14ARF protein expressed in bacteria.
Subclass IgG2a
Positive Control BT549 breast cancer cell line.
Molecular Weight (kDa) 14
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Cancer, Cell Cycle, Epigenetics & Nuclear Signalling

References: 8 entries

Ma et al. 2007. Mol Biol Cell. 18(7):2630-5. PMID: 17494866.

Depletion of the nucleolar protein nucleostemin causes G1 cell cycle arrest via the p53 pathway.

Europe PMC ID: 17494866

p14ARF expression in invasive breast cancers and ductal carcinoma in situ--relationships to p53 and Hdm2.

Europe PMC ID: 15318938

Vestey et al. 2004. Breast Cancer Res. 6(5):R571-85. PMID: 15318938.

IHC

Clark et al. 2002. Oncogene. 21(29):4498-507. PMID: 12085228.

Multiple interacting domains contribute to p14ARF mediated inhibition of MDM2.

Europe PMC ID: 12085228

Llanos et al. 2001. Nat Cell Biol. 3(5):445-52. PMID: 11331871.

IF

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

Europe PMC ID: 11331871


Add a reference

References: 8 entries

Ma et al. 2007. Mol Biol Cell. 18(7):2630-5. PMID: 17494866.

Depletion of the nucleolar protein nucleostemin causes G1 cell cycle arrest via the p53 pathway.

Europe PMC ID: 17494866

p14ARF expression in invasive breast cancers and ductal carcinoma in situ--relationships to p53 and Hdm2.

Europe PMC ID: 15318938

Vestey et al. 2004. Breast Cancer Res. 6(5):R571-85. PMID: 15318938.

IHC

Clark et al. 2002. Oncogene. 21(29):4498-507. PMID: 12085228.

Multiple interacting domains contribute to p14ARF mediated inhibition of MDM2.

Europe PMC ID: 12085228

Llanos et al. 2001. Nat Cell Biol. 3(5):445-52. PMID: 11331871.

IF

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

Europe PMC ID: 11331871


Add a reference

References: 8 entries

Ma et al. 2007. Mol Biol Cell. 18(7):2630-5. PMID: 17494866.

Depletion of the nucleolar protein nucleostemin causes G1 cell cycle arrest via the p53 pathway.

p14ARF expression in invasive breast cancers and ductal carcinoma in situ--relationships to p53 and Hdm2.

Vestey et al. 2004. Breast Cancer Res. 6(5):R571-85. PMID: 15318938.

IHC

Clark et al. 2002. Oncogene. 21(29):4498-507. PMID: 12085228.

Multiple interacting domains contribute to p14ARF mediated inhibition of MDM2.

Llanos et al. 2001. Nat Cell Biol. 3(5):445-52. PMID: 11331871.

IF

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.


Add a reference


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