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Anti-S100A8 [7C12/4]


Catalogue Number 151240
Applications ELISA FACS IHC WB
Antigen/Gene or Protein Targets S100A8 (MRP8)
Reactivity Human
Relevance S100A8 and S100A9 are cytosolic calcium-binding proteins of 8kDa and 14kDa respectively that form a heterodimer. S100A8 and S100A9 are expressed in peripheral blood monocytes, neutrophils and keratinocytes (mature). Expression is lost on tissue maturation of monocytes to macrophages. S100A9 may be associated with monocyte and neutrophil activation and the accumulation of these cells in inflammatory sites.
Host Mouse
Immunogen Recombinant human S100A8
Subclass IgM
Positive Control Neutrophil lysate (from spleen)
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions RPMI 1640 (2% Bicarbonate) plus 10% Foetal Calf Serum.
Strain Balb/c
Research Area Cancer, Cell Type or Organelle Marker, Neurobiology

References: 1 entry

Robinson et al. 2002. J Biol Chem. 277(5):3658-65. PMID: 11723110.

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