Anti-HLADRb [TDR 31.1]
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 151230 |
| Applications | ELISA FACS RIA |
| Antigen/Gene or Protein Targets | Human Leukocyte Antigen DR, beta chain, monomorphic. |
| Reactivity | Human |
| Relevance | Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TDR 31.1 can be used for the identification of class II HLA molecules. |
| Host | Mouse |
| Immunogen | Ia fraction from Jy human B lymphoblastoid cell line. Class II from JY human B lymphoblastoid cell line. |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 29 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS. |
| Notes | TDR 31.1 can detect both dimer and the beta chain by western blot. |
| Research Area | Immunology |
References: 4 entries
de Kretser et al. 1982. Eur J Immunol. 12(3):214-21. PMID: 6178597.
Demonstration of two distinct light chains in HLA-DR-associated antigens by two-dimensional gel electrophoresis.
Europe PMC ID: 6178597
Brodsky et al. 1979. Immunol Rev. 47:3-61. PMID: 95015.
Monoclonal antibodies for analysis of the HLA system.
Europe PMC ID: 95015
Add a reference
References: 4 entries
de Kretser et al. 1982. Eur J Immunol. 12(3):214-21. PMID: 6178597.
Demonstration of two distinct light chains in HLA-DR-associated antigens by two-dimensional gel electrophoresis.
Brodsky et al. 1979. Immunol Rev. 47:3-61. PMID: 95015.
Monoclonal antibodies for analysis of the HLA system.
Add a reference
