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Anti-HLADRb [TDR 31.1]

Info

Catalogue Number 151230
Applications ELISA FACS RIA
Antigen/Gene or Protein Targets Human Leukocyte Antigen DR, beta chain, monomorphic.
Reactivity Human
Relevance Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TDR 31.1 can be used for the identification of class II HLA molecules.
Host Mouse
Immunogen Ia fraction from Jy human B lymphoblastoid cell line. Class II from JY human B lymphoblastoid cell line.
Subclass IgG1
Molecular Weight (kDa) 29
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS.
Notes TDR 31.1 can detect both dimer and the beta chain by western blot.
Research Area Immunology

References: 2 entries

de Kretser et al. 1982. Eur J Immunol. 12(3):214-21. PMID: 6178597.

Brodsky et al. 1979. Immunol Rev. 47:3-61. PMID: 95015.


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