Catalogue Number
|
151229 |
Applications
|
ELISA
FACS
IHC
RIA
WB
|
Antigen/Gene or Protein Targets
|
Human Leukocyte Antigens DR3, 6, 11, DRJ25
|
Reactivity
|
Human
|
Relevance
|
Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TAL 8.1 may be used for HLA typing.
|
Host
|
Mouse
|
Immunogen
|
Cells from the B line WVB coated with mouse antiserum followed by WVB class II antigen.
|
Subclass
|
IgG2b
|
Molecular Weight (kDa)
|
28
|
Myeloma Used
|
P3/NS1/1-Ag4.1
|
Recommended Growing Conditions
|
RPMI 1640 + 10% FCS
|
Notes
|
TAL 8.1 can detect dimers via western blot and is cytotoxic with rabbit complement.
|
Research Area
|
Immunology
|