Anti-HLADRa [TAL 1B5]
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (10)
- Inventor Info
Info
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| Catalogue Number | 151227 |
| Applications | ELISA FACS IHC IF RIA WB |
| Antigen/Gene or Protein Targets | Human Leukocyte Antigen DR, alpha subunit |
| Reactivity | Human |
| Relevance | Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TAL 1B5 may be used for HLA typing. |
| Host | Mouse |
| Immunogen | Bristol 8 separated alpha chain preparation |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 33 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS |
| Notes | TAL 1B5 can detect both dimers and the DR alpha chain by western blot. |
| Research Area | Immunology |
References: 10 entries
Roher et al. 2013. PLoS One. 8(3):e59735. PMID: 23555764.
Bapineuzumab alters aβ composition: implications for the amyloid cascade hypothesis and anti-amyloid immunotherapy.
Europe PMC ID: 23555764
Chung et al. 2012. Int J Cancer. 131(3):E227-35. PMID: 22174092.
Tumor-associated macrophages correlate with response to epidermal growth factor receptor-tyrosine kinase inhibitors in advanced non-small cell lung cancer.
Europe PMC ID: 22174092
van Dongen et al. 2010. Int J Cancer. 127(4):899-909. PMID: 20013807.
Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor-treated gastrointestinal stromal tumors.
Europe PMC ID: 20013807
Thomas et al. 1988. J Pathol. 154(4):353-63. PMID: 2455029.
IHC
HLA-D region alpha-chain monoclonal antibodies: cross-reaction between an anti-DP alpha-chain antibody and smooth muscle.
Europe PMC ID: 2455029
Adams et al. 1983. Immunology. 50(4):613-24. PMID: 6197354.
Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens.
Europe PMC ID: 6197354
Add a reference
References: 10 entries
Roher et al. 2013. PLoS One. 8(3):e59735. PMID: 23555764.
Bapineuzumab alters aβ composition: implications for the amyloid cascade hypothesis and anti-amyloid immunotherapy.
Chung et al. 2012. Int J Cancer. 131(3):E227-35. PMID: 22174092.
Tumor-associated macrophages correlate with response to epidermal growth factor receptor-tyrosine kinase inhibitors in advanced non-small cell lung cancer.
van Dongen et al. 2010. Int J Cancer. 127(4):899-909. PMID: 20013807.
Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor-treated gastrointestinal stromal tumors.
Thomas et al. 1988. J Pathol. 154(4):353-63. PMID: 2455029.
IHC
HLA-D region alpha-chain monoclonal antibodies: cross-reaction between an anti-DP alpha-chain antibody and smooth muscle.
Adams et al. 1983. Immunology. 50(4):613-24. PMID: 6197354.
Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens.
Add a reference
