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Anti-HLADRa [TAL 1B5]

Info

Catalogue Number 151227
Applications ELISA FACS IHC IF RIA WB
Antigen/Gene or Protein Targets Human Leukocyte Antigen DR, alpha subunit
Reactivity Human
Relevance Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TAL 1B5 may be used for HLA typing.
Host Mouse
Immunogen Bristol 8 separated alpha chain preparation
Subclass IgG1
Molecular Weight (kDa) 33
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS
Notes TAL 1B5 can detect both dimers and the DR alpha chain by western blot.
Research Area Immunology

References

There are 10 reference entries for this reagent.

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References: 10 entries

Roher et al. 2013. PLoS One. 8(3):e59735. PMID: 23555764.

Bapineuzumab alters aβ composition: implications for the amyloid cascade hypothesis and anti-amyloid immunotherapy.

Europe PMC ID: 23555764

Chung et al. 2012. Int J Cancer. 131(3):E227-35. PMID: 22174092.

Tumor-associated macrophages correlate with response to epidermal growth factor receptor-tyrosine kinase inhibitors in advanced non-small cell lung cancer.

Europe PMC ID: 22174092

van Dongen et al. 2010. Int J Cancer. 127(4):899-909. PMID: 20013807.

Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor-treated gastrointestinal stromal tumors.

Europe PMC ID: 20013807

Thomas et al. 1988. J Pathol. 154(4):353-63. PMID: 2455029.

IHC

HLA-D region alpha-chain monoclonal antibodies: cross-reaction between an anti-DP alpha-chain antibody and smooth muscle.

Europe PMC ID: 2455029

Adams et al. 1983. Immunology. 50(4):613-24. PMID: 6197354.

Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens.

Europe PMC ID: 6197354


Add a reference

References: 10 entries

Roher et al. 2013. PLoS One. 8(3):e59735. PMID: 23555764.

Bapineuzumab alters aβ composition: implications for the amyloid cascade hypothesis and anti-amyloid immunotherapy.

Chung et al. 2012. Int J Cancer. 131(3):E227-35. PMID: 22174092.

Tumor-associated macrophages correlate with response to epidermal growth factor receptor-tyrosine kinase inhibitors in advanced non-small cell lung cancer.

van Dongen et al. 2010. Int J Cancer. 127(4):899-909. PMID: 20013807.

Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor-treated gastrointestinal stromal tumors.

Thomas et al. 1988. J Pathol. 154(4):353-63. PMID: 2455029.

IHC

HLA-D region alpha-chain monoclonal antibodies: cross-reaction between an anti-DP alpha-chain antibody and smooth muscle.

Adams et al. 1983. Immunology. 50(4):613-24. PMID: 6197354.

Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens.


Add a reference

Inventor Information