Anti-HLADQ3, DQ4 & DR4 [TAL 12.1]
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151226 |
| Applications | ELISA FACS WB |
| Antigen/Gene or Protein Targets | Human Leukocyte Antigens DQ3 , DQ4 & DR4 |
| Reactivity | Human |
| Relevance | Human Leukocyte Antigens (HLA) are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TAL 12.1 may be used for HLA typing. |
| Host | Mouse |
| Subclass | IgG2b |
| Myeloma Used | NS0 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS |
| Notes | TAL 12.1 detects the dimer only by western blot and is cytotoxic with rabbit complement. |
| Research Area | Immunology |
References: 2 entries
Bodmer et al. 1989. Cold Spring Harb Symp Quant Biol. 54 Pt 1:471-6. PMID: 2484167.
Monoclonal antibodies and the epitope distribution of HLA class II polymorphisms.
Europe PMC ID: 2484167
Add a reference
References: 2 entries
Bodmer et al. 1989. Cold Spring Harb Symp Quant Biol. 54 Pt 1:471-6. PMID: 2484167.
Monoclonal antibodies and the epitope distribution of HLA class II polymorphisms.
Add a reference