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Anti-HLADR ß chain 1 [DA2]


Catalogue Number 151225
Applications ELISA FACS IHC WB
Antigen/Gene or Protein Targets Human Leukocyte Antigen DR ß chain 1 (1st domain, monomorphic, MHC class II)
Reactivity Human
Relevance Human Leukocyte Antigens (HLA) are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). DA2 may be used for tissue typing.
Host Mouse
Immunogen The membranes of LKT cells (a B lymphoblastoid cell line)
Subclass IgG1
Myeloma Used P3X63Ag8
Recommended Growing Conditions RPMI 1640 + 10% FCS
Strain Balb/c
Notes DA2 will detect dimers and the beta chain by western blot. DA2 will bind all DR and DP antigens except DR7.
Research Area Immunology

References: 2 entries

Brodsky et al. 1980. Tissue Antigens. 16(1):30-48. PMID: 6162228.

Brodsky et al. 1979. Immunol Rev. 47:3-61. PMID: 95015.

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