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Catalogue Number 151220
Applications IHC IF IP WB
Antigen/Gene or Protein Targets Platelet-derived endothelial cell growth factor (thymidine phosphorylase); PD-ECGF.
Reactivity Human
Relevance PD-ECGF expression is elevated in breast tumours and is a prognostic factor in colon tumours.
Host Mouse
Immunogen Full length human protein in E. coli
Subclass IgG1
Positive Control HUVEC cell or breast carcinoma
Molecular Weight (kDa) 55 (reduced)
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions DMEM + 5% FCS
Notes PGF 44C blocks enzyme activity.
Research Area Cancer, Cardiovascular, Immunology

References: 6 entries

Weng et al. 2012. Basic Clin Pharmacol Toxicol. 110(3):298-306. PMID: 21973306.

Ko et al. 2011. J Pharmacol Exp Ther. 338(1):184-94. PMID: 21444628.

Giatromanolaki et al. 2003. J Pathol. 200(2):222-8. PMID: 12754744.

Fox et al. 1997. Ann Oncol. 8(3):271-5. PMID: 9137797.

Fox et al. 1995. J Pathol. 176(2):183-90. PMID: 7636628.

Moghaddam et al. 1995. Proc Natl Acad Sci U S A. 92(4):998-1002. PMID: 7532308.

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