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Anti-ACTR2 [149/1]

Invented by Prof Roy Bicknell at University Of Birmingham

Info

Catalogue Number 151217
Applications IHC IF IP WB
Antigen/Gene or Protein Targets Activin receptor type 2 (ACTR2)
Reactivity Human
Relevance ACTR2 is a serine/threonine kinase receptor. Activin signal transduction pathways are implicated in diverse developmental and physiological processes. Activin is implicated in control of vascular endothelial growth.
Host Mouse
Immunogen Recombinant fusion protein composed of the intracellular kinase domain of the human type 2 activin receptor fused to gluthathion S-transferase
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions DMEM + 5% FCS. Thaw into DMEM + 10% FCS and 10% Iscoves and reduce to DMEM + 5% FCS
Strain Balb/c
Research Area Cardiovascular, Cell Signaling & Signal Transduction, Cell Structure and Motility, Developmental Biology

References: 6 entries

Zhu et al. 2007. J Neurosci. 27(50):13770-80. PMID: 18077689.

IF WB

Activin acutely sensitizes dorsal root ganglion neurons and induces hyperalgesia via PKC-mediated potentiation of transient receptor potential vanilloid I.

Europe PMC ID: 18077689

McCarthy et al. 1994. Hybridoma. 13(3):199-203. PMID: 7927363.

Monoclonal antibodies that recognize the type-2 activin receptor, ACTR2.

Europe PMC ID: 7927363

McCarthy et al. 1994. J Biol Chem. 269(6):3909-12. PMID: 8307945.

Activin-A binds to a heterotrimeric receptor complex on the vascular endothelial cell surface. Evidence for a type 3 activin receptor.

Europe PMC ID: 8307945


Add a reference

References: 6 entries

Zhu et al. 2007. J Neurosci. 27(50):13770-80. PMID: 18077689.

IF WB

Activin acutely sensitizes dorsal root ganglion neurons and induces hyperalgesia via PKC-mediated potentiation of transient receptor potential vanilloid I.

Europe PMC ID: 18077689

McCarthy et al. 1994. Hybridoma. 13(3):199-203. PMID: 7927363.

Monoclonal antibodies that recognize the type-2 activin receptor, ACTR2.

Europe PMC ID: 7927363

McCarthy et al. 1994. J Biol Chem. 269(6):3909-12. PMID: 8307945.

Activin-A binds to a heterotrimeric receptor complex on the vascular endothelial cell surface. Evidence for a type 3 activin receptor.

Europe PMC ID: 8307945


Add a reference

References: 6 entries

Zhu et al. 2007. J Neurosci. 27(50):13770-80. PMID: 18077689.

IF WB

Activin acutely sensitizes dorsal root ganglion neurons and induces hyperalgesia via PKC-mediated potentiation of transient receptor potential vanilloid I.

McCarthy et al. 1994. Hybridoma. 13(3):199-203. PMID: 7927363.

Monoclonal antibodies that recognize the type-2 activin receptor, ACTR2.

McCarthy et al. 1994. J Biol Chem. 269(6):3909-12. PMID: 8307945.

Activin-A binds to a heterotrimeric receptor complex on the vascular endothelial cell surface. Evidence for a type 3 activin receptor.


Add a reference


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